we should have a well knowing of the relationship between pregnancy and Nephrotic Syndrome.
1. The types of Nephrotic Syndrome in pregnancy
Nephrotic Syndrome in pregnancy can be divided into four types:
· Nephrotic Syndrome associated with pre-eclampsia
It is the most common type of Nephrotic Syndrome in pregnancy.
· Cyclic Nephrotic Syndrome of Pregnancy
Its characteristic is it will attack in the duration of pregnancy, and will remit spontaneously after the pregnancy terminates. However, it will relapse when the women are pregnant once again. This type is rarely seen.
· Chronic Glomerulonephritis accompanied by pregnancy
For women with this type Nephrotic Syndrome, the women must have a medical history of Nephritis, or it is found for the first time during the period of pregnancy.
· Secondary Nephrotic Syndrome
It is caused by pregnancy combined with other reasons. And it can be seen in Lupus Nephritis, Diabetic Nephropathy, Renal Vein Thrombosis and others.
2. The physiological changes of the kidneys in pregnancy
A. The morphological changes of the kidneys
· In the period of pregnancy, the size and the weight of the kidneys will both increase.
· The collecting duct system of the kidneys will have obvious changes.
B. The changes of the renal functions
In the period of pregnancy, the effective renal plasma flow(ERPF) and the glomerular filtration rate(GFR) of the kidneys will increase significantly.
The increase of the GFR will change the normal biochemical values. If the value of serum creatinine, urea nitrogen(BUN) and uric acid(UA) respectively excesses 70.7 µmol/L, 4.64 mmol/L and 268 µmol/L, then it is abnormal.
The increase of the ERPF and GFR will make the glomeruli be in a state of hyperperfusion and hyperfiltration. For pregnant women with kidney disease and Hypertension, such kind physiological change are definite risk factor, which will lead to and accelerate the sclerosis of the glomeruli and the worsening of the kidney function.
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2011年10月17日星期一
A Brief Introduction of the Renal Function Test
For patients who have Nephrotic Syndrome or other kidney disease, renal function test is necessary for them, because they need to monitor the progression of their condition. And according to the changes of their condition, the nephrologist can adjust the treatment timely, thus the patients who have Nephrotic Syndrome or other kidney disease can achieve a better curative effect. The following is a brief introduction of the renal function test, may it can help you know more about your condition.
Generally, the renal function test includes serum creatinine(Scr), blood urea nitrogen(BUN) and uric acid(UA). These tests are achieved by blood test. Therefore, three days before doing the tests, you'd better have a vegetarian diet and avoid strenuous exercise, or at least do not eat high-protein food and large amounts of meat the night before draw blood, so as to insure the accuracy of the tests.
The change of the serum creatinine concentration can be used to evaluate the function of the glomeruli. However, as the compensation of the kidney is powerful, after part of the glomeruli have been damaged, the rest still can remove the creatinine effectively. As a result, the serum creatinine is not sensitive to the changes of the renal function, and only when the glomerular filtration rate reduces 50%, the serum creatinine will begin to increase, so it is not accurate if we only use serum creatinine to judge the renal function.
Uric acid is the metabolite of purine, and the blood uric acid is also an index for evaluating the renal function.
Blood urea nitrogen can be affected by many factors including the diet, so it also can not reflect the real condition of the renal function accurately.
Therefore, in order to make an early detection of the abnormal filtration function of the glomeruli, endogenous creatinine clearance rate(Ccr) is developed. Three days before doing the endogenous creatinine clearance test, you'd better take a vegetarian diet, and avoid large amounts of meat and strenuous exercise.
At present, the most accurate and convenient method for evaluating the renal function is using the Cockcroft formula:
· for males: Ccr(ml/min)=[(140-age)*88.4]/(72*Scr)
· for females: Ccr(ml/min)=[(140-age)*88.4*0.85]/(72*Scr)
The normal value of Ccr is 80~120 ml/min. The aforementioned formula is not appropriate for people of special body type and children. As for children, the following formula is appropriate: Ccr(ml/min)=[0.43*height(cm)*88.4]/Scr(umol/L).
The aforementioned is the brief introduction of the renal function test. Patients with Nephrotic Syndrome or other kidney disease should do the renal function test regularly so as to receive timely treatment.
Characteristic Therapy of Childhood Nephrotic Syndrome
I. Western Medicine
Western Medicine mainly includes symptomatic treatment, conventional treatment, immunosuppressive therapy, hormone and
and other treatments. All these treatments can treat Childhood Nephrotic Syndrome effectively in a short time, but they can not treat this disease fundamentally, thus this disease is easy to relapse.
II. Traditional Chinese Medicine
Traditional Chinese Medicine can treat Childhood Nephrotic Syndrome fundamentally. However, it takes effect slowly, thus causing the course of treatment is long. And it has toxic effects on the whole body by taking large quantities of oral Chinese Medicines. Therefore, Traditional Chinese Medicine is not an ideal treatment for patients either.
III. Micro-Chinese Medicine Osmotherapy
Childhood Nephrotic Syndrome is more common in children between ages of 3~6. The cause of this disease is not clear yet. And this disease is easy to relapse and deteriorate. Therefore, all these characteristics of Childhood Nephrotic Syndrome indicate that this disease can affect the children's growth and development greatly in their whole life. And the side effect of hormone is great, which can also affect the children's life. For example, moon face, a symptom which will make the children feel depressed, especially when after a long-term hormone treatment, there is not a thing in the world to make it go away.
Therefore, a characteristic therapy is necessary, which can treat Childhood Nephrotic Syndrome fundamentally, and has less side effects. Micro-Chinese Medicine Osmotherapy in our hospital is such a kind treatment.
The core technology of Micro-Chinese Medicine Osmotherapy is to make the effective prescriptions of Childhood Nephrotic Syndrome superfinely shattered. Then with the help of effective penetrant and osmosis devices, the effective medicines are permeated into kidney lesions by external application, thus achieving the goal of treating Childhood Nephrotic Syndrome.
The characteristics of Micro-Chinese Medicine Osmotherapy in treating Childhood Nephrotic Syndrome are as follows:
1. More convenient and much easier
This treatment can not only avoid the toxic effects caused by taking large quantities of oral Chinese Medicines, but also can solve the shortcomings(symptomatic treatment) of West Medicines effectively. By this treatment, children just need to lie in bed adopting the treatment without taking medicines and getting an injection. Thus, this treatment is preferred by children because of the aforementioned characteristic.
2. Taking effect more quickly
After being refined, the molecular volume of the Micro-Chinese Medicine is extremely small. Therefore, the medicine molecules can penetrate the glomerular basilar membrane, and then reach the lesions, taking effects of blocking the kidney fibrosis, repairing the damaged renal intrinsic cells and rebuilding the normal kidney structure quickly. In addition it can also remit the hematuria and the leakage of protein in a short time. Generally, after the treatment of Micro-Chinese Medicine Osmotherapy, some changes of the symptoms will occur in patients who are sensitive to the Traditional Chinese Medicine.
3. A thorough treatment
The Micro-Chinese Medicine is aiming at protecting the kidney by repairing the renal intrinsic cells and blocking the kidney fibrosis, thus eliminating the hematuria and the leakage of protein thoroughly.
In a word, Micro-Chinese Medicine Osmotherapy is more effective and more suitable in treating Childhood Nephrotic Syndrome.2011年10月13日星期四
Effects and Side Effects of Hormonal Therapy in Treating Minimal Change Disease
Conventional dose of hormone treatment: Prednisone 60mg/m2/d for children and 40~60mg/d for adults with a gradual decrement in 4 ~6 months. It will take effect in 4 weeks for 90% of children patients and in 8 weeks for 90% adults. If massive proteinuria still exists, immunosuppressant should be added to the treatment.
About 50% of those who are sensitive to hormone can maintain negative proteinuria or relapse after drug reduction or withdrawal, but most of the patients will finally remit. The other 50% of the patients often relapse or present hormonal dependence which means that larger dose of hormone is needed to control proteinuria. At this time, side effects of hormone often occur and are more obvious in children patients. Daily addition of Cyclophosphamide 2~3mg/kg (75mg/m2 for children) in the treatment for 8~12 weeks will prolong the paracmasia of patients who are sensitive to hormone. Because of the toxicity to gonad, teratology and other toxic reactions, cytotoxic drugs can only be applied when the kidney disease and side effects of hormone are both severe. In cases where hormone is effective but recurrent attacks are often or there is dependence to hormone, and moreover, there is no indicator for application of cytotoxic preparation Cyclophosphamide, Ciclosporin A can be applied in such cases. Orally taking Ciclosporin with a dose of 3.5~4mg/(kg·d), most patients with MCD can have remission of their symptoms. The there can be a significant reduction of hormone.
When Nephrotic Syndrome caused by MCD cannot remit through the above treatment, the following should be paid attention to:
(1) Control or remove the infection focus especially the latent infection focus.
(2) Renal venous thrombosis. Conduct CT in time and when there is renal venous thrombosis for final diagnosis, Urokinase of 40~80 thousand u/d adding to 0.9% Sodium Chloride 40ml can be used by intravenous injection 1~2 times/d. Early diagnosis of renal venous thrombosis and positive anticoagulant therapy can improve the condition of primary glomerulopathy and prognosis of various primary glomerulonephritis.
(3) Patients who are not sensitive to hormone often have focal glomeruloslcerosis.
(4) In order to reduce recurrence rate after withdrawal of hormone, concentration of blood Cortisone should be determined before withdrawal of hormone. Patients with normal concentration of blood Cortisone are not easy to relapse.
About 50% of those who are sensitive to hormone can maintain negative proteinuria or relapse after drug reduction or withdrawal, but most of the patients will finally remit. The other 50% of the patients often relapse or present hormonal dependence which means that larger dose of hormone is needed to control proteinuria. At this time, side effects of hormone often occur and are more obvious in children patients. Daily addition of Cyclophosphamide 2~3mg/kg (75mg/m2 for children) in the treatment for 8~12 weeks will prolong the paracmasia of patients who are sensitive to hormone. Because of the toxicity to gonad, teratology and other toxic reactions, cytotoxic drugs can only be applied when the kidney disease and side effects of hormone are both severe. In cases where hormone is effective but recurrent attacks are often or there is dependence to hormone, and moreover, there is no indicator for application of cytotoxic preparation Cyclophosphamide, Ciclosporin A can be applied in such cases. Orally taking Ciclosporin with a dose of 3.5~4mg/(kg·d), most patients with MCD can have remission of their symptoms. The there can be a significant reduction of hormone.
When Nephrotic Syndrome caused by MCD cannot remit through the above treatment, the following should be paid attention to:
(1) Control or remove the infection focus especially the latent infection focus.
(2) Renal venous thrombosis. Conduct CT in time and when there is renal venous thrombosis for final diagnosis, Urokinase of 40~80 thousand u/d adding to 0.9% Sodium Chloride 40ml can be used by intravenous injection 1~2 times/d. Early diagnosis of renal venous thrombosis and positive anticoagulant therapy can improve the condition of primary glomerulopathy and prognosis of various primary glomerulonephritis.
(3) Patients who are not sensitive to hormone often have focal glomeruloslcerosis.
(4) In order to reduce recurrence rate after withdrawal of hormone, concentration of blood Cortisone should be determined before withdrawal of hormone. Patients with normal concentration of blood Cortisone are not easy to relapse.
2011年10月12日星期三
Dietary Limitation for Patients with Hypertensive Nephropathy
1. Protein foods
What NOT to eat: processed food such as sausage, and foods high in fat such as streaky pork, beef, whale meat, ribchop, eel, tunny and menhaden
Though these foods contain high protein, their content of saturated fatty acid is also very high, which will cause high level of blood lipid and finally induce Coronary Heart Disease
2. Carbohydrate foods
What NOT to eat: dry beans, sweet potatoes and biscuits of strong taste
As dry beans and sweet potatoes can easily lead to flatulence, patients with Hypertensive Nephropathy had better not eat the two kind food. And biscuits of strong taste contain much sugar and sodium, so they are also not appropriate for patients.
3. Fat foods
What NOT to eat: animal oil, bacon
4. Foods high in vitamins and mineral substance
What NOT to eat: condiment vegetables such as celery, leaf mustard and green onion, and vegetables containing hard fibre such as bamboo shoots and corn
5. Other foods
What NOT to eat: spices such as mustard, curry powder and hot pepper, alcoholic drinks, coffee, strong black tea, carbonated beverage, pickled foods such as salted fish roe, salted salmon and pickles
What NOT to eat: processed food such as sausage, and foods high in fat such as streaky pork, beef, whale meat, ribchop, eel, tunny and menhaden
Though these foods contain high protein, their content of saturated fatty acid is also very high, which will cause high level of blood lipid and finally induce Coronary Heart Disease
2. Carbohydrate foods
What NOT to eat: dry beans, sweet potatoes and biscuits of strong taste
As dry beans and sweet potatoes can easily lead to flatulence, patients with Hypertensive Nephropathy had better not eat the two kind food. And biscuits of strong taste contain much sugar and sodium, so they are also not appropriate for patients.
3. Fat foods
What NOT to eat: animal oil, bacon
4. Foods high in vitamins and mineral substance
What NOT to eat: condiment vegetables such as celery, leaf mustard and green onion, and vegetables containing hard fibre such as bamboo shoots and corn
5. Other foods
What NOT to eat: spices such as mustard, curry powder and hot pepper, alcoholic drinks, coffee, strong black tea, carbonated beverage, pickled foods such as salted fish roe, salted salmon and pickles
2011年10月11日星期二
The 13 crew in the golden triangle area recruit crazy genocide
In 2001, China, Myanmar, Thailand and Laos signed an agreement after the navigation, the navigation of this river is beginning to normalization. Pass on to all peoples of the economic convenience, also makes this international river shipping to regular.
Yet that Jiangzhi An extremely chaotic, 2007, killing a Chinese crew, these are some local militants. Often harass Chinese ships.
In early 2011, there was a crew of 20 people abducted Chinese things.
But has not been a good deal.
October 5, 2011, a group of armed hijacking of two ships. A Chinese ship (Warburg Pincus), and Burmese vessels (Yu Xing 8), two ships full of the China crew. The armed men forced two ships fled to Thailand at full capacity.
Thailand's Chiang Saen port 10 km away from the place, met Thai maritime police in the hunt. The two sides exchanged fire.
Thai police on the water after two ships, in addition to No. 8 Xing Yu a body outside the living room. The ship no one.
Crew missing.
Yet that Jiangzhi An extremely chaotic, 2007, killing a Chinese crew, these are some local militants. Often harass Chinese ships.
In early 2011, there was a crew of 20 people abducted Chinese things.
But has not been a good deal.
October 5, 2011, a group of armed hijacking of two ships. A Chinese ship (Warburg Pincus), and Burmese vessels (Yu Xing 8), two ships full of the China crew. The armed men forced two ships fled to Thailand at full capacity.
Thailand's Chiang Saen port 10 km away from the place, met Thai maritime police in the hunt. The two sides exchanged fire.
Thai police on the water after two ships, in addition to No. 8 Xing Yu a body outside the living room. The ship no one.
Crew missing.
2011年10月10日星期一
Treating Nephrotic Syndrome without Using Hormone Therapy?
I. How to regard hormone therapy in treating Nephrotic Syndrome?
We all know that hormone therapy is commonly used in treating kidney diseases including Nephrotic Syndrome. The reason is that hormone does have the effect of controlling the disease in a short time. However, many patients with kidney disease will turn pale at the mention of hormone. The reason lies in its side effects and its only curing the symptoms instead of the disease which will cause relapse of the disease once and again. Therefore, we shouldn’t arbitrarily judge hormone as good or bad. Moreover, we should use it carefully, such as avoiding stopping using it suddenly; otherwise, it will easily cause many side effects.
II. To make out whether we can treat NS without hormone, we should also know the pathogenesis of NS and how hormone takes effect in treating this disease.
Nephrotic Syndrome is a group of glomerulopathy that has similar pathological changes and clinical manifestations. The main changes are strengthened permeability of the glomerular membrane and decrease of GFR (Glomerular Filtration Rate). The typical manifestations include massive proteinuria, Hypoproteinemia, severe edema and Hyperlipemia.
Then how does hormone take effect in treating NS? Hormone has the function of inhibiting immunocytes and organic immunoreaction, so it can reduce damage of the renal intrinsic cells by immune complex. At the same time, it can protect intercellular matrix by balancing generation and degradation of polysaccharide. So hormone can effectively control the progress of the disease, especially the acute and active stage of NS.
Different pathological types of primary Nephrotic Syndrome should be treated with different application method of hormone, but the common adverse effect of it should be paid attention to: central obesity, high blood pressure, osteoporosis; digestive tract symptoms like nausea, vomiting and stress ulcer; spiritual symptoms like insomnia and excitation.
III. New therapy of treating Nephrotic Syndrome—significant effect of Micro-Chinese Medicine
Here, we can see that it is not easy to get rid of hormone completely. But don’t get discouraged, we have an effective way of avoid the side effects of hormone to a large extent—to combine hormone therapy with traditional Chinese medicine treatment, which has great power to reduce the side effects of hormone. Moreover, traditional Chinese medicine also has good curative effect in treating NS.
We all know that hormone therapy is commonly used in treating kidney diseases including Nephrotic Syndrome. The reason is that hormone does have the effect of controlling the disease in a short time. However, many patients with kidney disease will turn pale at the mention of hormone. The reason lies in its side effects and its only curing the symptoms instead of the disease which will cause relapse of the disease once and again. Therefore, we shouldn’t arbitrarily judge hormone as good or bad. Moreover, we should use it carefully, such as avoiding stopping using it suddenly; otherwise, it will easily cause many side effects.
II. To make out whether we can treat NS without hormone, we should also know the pathogenesis of NS and how hormone takes effect in treating this disease.
Nephrotic Syndrome is a group of glomerulopathy that has similar pathological changes and clinical manifestations. The main changes are strengthened permeability of the glomerular membrane and decrease of GFR (Glomerular Filtration Rate). The typical manifestations include massive proteinuria, Hypoproteinemia, severe edema and Hyperlipemia.
Then how does hormone take effect in treating NS? Hormone has the function of inhibiting immunocytes and organic immunoreaction, so it can reduce damage of the renal intrinsic cells by immune complex. At the same time, it can protect intercellular matrix by balancing generation and degradation of polysaccharide. So hormone can effectively control the progress of the disease, especially the acute and active stage of NS.
Different pathological types of primary Nephrotic Syndrome should be treated with different application method of hormone, but the common adverse effect of it should be paid attention to: central obesity, high blood pressure, osteoporosis; digestive tract symptoms like nausea, vomiting and stress ulcer; spiritual symptoms like insomnia and excitation.
III. New therapy of treating Nephrotic Syndrome—significant effect of Micro-Chinese Medicine
Here, we can see that it is not easy to get rid of hormone completely. But don’t get discouraged, we have an effective way of avoid the side effects of hormone to a large extent—to combine hormone therapy with traditional Chinese medicine treatment, which has great power to reduce the side effects of hormone. Moreover, traditional Chinese medicine also has good curative effect in treating NS.
2011年10月9日星期日
How does Stem Cell Transplant Treat Diabetes?
I. Stem cell could repair islet beta cells
Islet beta cells are mainly in charge of producing insulin. Stem cell could repair pancreas islet, and then pancreas islet could produce new islet beta cells; the repaired islet beta cells will own function of producing insulin;
II. Stem cell could repair other insulin-producing cells
There are also some other insulin-producing cells in other organs and tissues except islet beta cells. Taking advantage of repairing and rebuilding functions of stem cells can increase secretion volume of insulin and play a role in blood sugar decrease.
III. Stem cell has an effect on Insulin Resistance
Stem cell transplant could increase the ability of transporting glycoprotein in cells, which could facilitate the combination of insulin receptor and insulin, and then decrease the resistance of insulin.
Stem Cell Transplant Treatment brings the hope to patients with Diabetes, and in the recent years, people pay more and more attention on Stem Cell Transplant Treatment. On the one hand, Stem Cell Transplant now is the most effective therapy to treat Diabetes; on the other hand, this therapy is side-effects free, rich in source and great in adaptability. More and more patients with Diabetes put their trust and hope on Stem Cell Transplant Treatment.
Islet beta cells are mainly in charge of producing insulin. Stem cell could repair pancreas islet, and then pancreas islet could produce new islet beta cells; the repaired islet beta cells will own function of producing insulin;
II. Stem cell could repair other insulin-producing cells
There are also some other insulin-producing cells in other organs and tissues except islet beta cells. Taking advantage of repairing and rebuilding functions of stem cells can increase secretion volume of insulin and play a role in blood sugar decrease.
III. Stem cell has an effect on Insulin Resistance
Stem cell transplant could increase the ability of transporting glycoprotein in cells, which could facilitate the combination of insulin receptor and insulin, and then decrease the resistance of insulin.
Stem Cell Transplant Treatment brings the hope to patients with Diabetes, and in the recent years, people pay more and more attention on Stem Cell Transplant Treatment. On the one hand, Stem Cell Transplant now is the most effective therapy to treat Diabetes; on the other hand, this therapy is side-effects free, rich in source and great in adaptability. More and more patients with Diabetes put their trust and hope on Stem Cell Transplant Treatment.
2011年10月8日星期六
Innovative Therapy in Treating Hypertensive Nephropathy
Since western medicine can not treat Hypertensive Nephropathy fundamentally and has obvious side effect, some patients begin to take Traditional Chinese Medicine into consideration. In fact, the curative effect of Traditional Chinese Medicine is good, and this disease can be treated from the root cause. In addition, Traditional Chinese Medicine has few side effects. However, generally, it will take a long time to show obvious curative effect, and few people like to take the oral Chinese herbal soup which has a bitter taste. Therefore, some people begin to wonder whether there is a kind of medicine which has no side effect, no bitter taste and also can treat Hypertensive Nephropathy fundamentally. The answer is "Yes". It is an innovative therapy in treating this disease.
On the one hand, it is aimed at improving the blood vessels at all levels, thus decreasing the blood pressure fundamentally. There are a large quantity of vasodilatation factors in the Traditional Chinese Medicine which has been superfinely shattered. The vasodilatation factors will enter into the tiny blood vessels, and can have a synergistic effect with the vascular tension factors, thus relaxing the blood vessels at all levels, and finally remitting the high blood pressure caused by insufficient diastole and overstrain of the blood vessels.
On the other hand, it is aimed at repairing the damaged nephron and improving the renal function. Once the superfinely-shattered medicines are permeated into our human body by external application, it will takes effect directly at the kidney lesions, thus repairing the damaged kidney and rebuilding the renal function. As the root cause has been removed, the high blood pressure will recover to normal naturally.
On the one hand, it is aimed at improving the blood vessels at all levels, thus decreasing the blood pressure fundamentally. There are a large quantity of vasodilatation factors in the Traditional Chinese Medicine which has been superfinely shattered. The vasodilatation factors will enter into the tiny blood vessels, and can have a synergistic effect with the vascular tension factors, thus relaxing the blood vessels at all levels, and finally remitting the high blood pressure caused by insufficient diastole and overstrain of the blood vessels.
On the other hand, it is aimed at repairing the damaged nephron and improving the renal function. Once the superfinely-shattered medicines are permeated into our human body by external application, it will takes effect directly at the kidney lesions, thus repairing the damaged kidney and rebuilding the renal function. As the root cause has been removed, the high blood pressure will recover to normal naturally.
2011年10月7日星期五
Eight Methods for Preventing Diabetic Nephropathy
Diabetic Nephropathy Should pay attention to what?
1. Drinking more water
It means the daily intake of water should be 1500~2000 ml.
2. Limiting the intake of protein and potassium
The intake of protein and potassium should be limited, including the foods and drinks which contains potassium. The daily intake of protein should be 0.6~0.8 g. And lean meat and fishes are appropriate.
3. Limiting the salt intake
Delicate diet is appropriate for patients with Diabetic Nephropathy. The salt intake should be not more than 6 g/d.
4. Controlling the blood sugar level
In order to control the blood sugar level, we should firstly limit the calorie intake, and then control the blood sugar. In addition, we should also avoid being emotional, infection and other factors which can cause the fluctuation of the blood sugar level.
5. Controlling the blood pressure
The blood pressure should be controlled lower than 130/80 mmHg.
6. Paying attention to the medicines
In some cases, Diabetic Nephropathy is induced by medicines which have renal toxicity. Therefore, for patients with Diabetic Nephropathy, the medicines should be taken under the guidance of the doctor.
7. Supplementing trace elements and vitamins
Patients should supplement enough trace elements and vitamins, especially vitamin C, vitamin B, zinc, calcium, and iron, for they can protect the kidneys.
8. Developing a good living habit
For patients with Diabetic Nephropathy, a good living habit is also of great importance. Patients should get rid of smoking, for it can aggravate their condition.
1. Drinking more water
It means the daily intake of water should be 1500~2000 ml.
2. Limiting the intake of protein and potassium
The intake of protein and potassium should be limited, including the foods and drinks which contains potassium. The daily intake of protein should be 0.6~0.8 g. And lean meat and fishes are appropriate.
3. Limiting the salt intake
Delicate diet is appropriate for patients with Diabetic Nephropathy. The salt intake should be not more than 6 g/d.
4. Controlling the blood sugar level
In order to control the blood sugar level, we should firstly limit the calorie intake, and then control the blood sugar. In addition, we should also avoid being emotional, infection and other factors which can cause the fluctuation of the blood sugar level.
5. Controlling the blood pressure
The blood pressure should be controlled lower than 130/80 mmHg.
6. Paying attention to the medicines
In some cases, Diabetic Nephropathy is induced by medicines which have renal toxicity. Therefore, for patients with Diabetic Nephropathy, the medicines should be taken under the guidance of the doctor.
7. Supplementing trace elements and vitamins
Patients should supplement enough trace elements and vitamins, especially vitamin C, vitamin B, zinc, calcium, and iron, for they can protect the kidneys.
8. Developing a good living habit
For patients with Diabetic Nephropathy, a good living habit is also of great importance. Patients should get rid of smoking, for it can aggravate their condition.
The Best Treatment for IgA Nephropathy
What is the best treatment for IgA nephropathy? What is it
IgA Nephropathy, a kind of primary glomerulopathy, is characterized by deposition of IgA in mesangial area and accounts for 20%~40% of primary glomerulopathy. Hematuria is the most typical symptom of IgA Nephropathy and there can also be other symptoms such as proteinuria and high blood pressure. Although IgA Nephropathy is not so well-known as Nephritis or Uremia, it is a rather common kidney disease and is one of the main causes of Renal Failure. Therefore, patients with IgA Nephropathy should take measures earlier to prevent their disease from deteriorating.
Clinically, there are various pathological types of IgA Nephropathy such as mesangial proliferative IgA Nephropathy, focal proliferative IgA Nephropathy and proliferative sclerosing IgA Nephropathy. No matter what kind of IgA Nephropathy, the prognosis will be influenced by three aspects: serum creatinine, blood pressure and 24h urine protein quantitation.
Generally, when one is diagnosed IgA Nephrpathy, the doctor will use hormone, cytotoxic drugs or immunosuppressant, but the effects are not so satisfactory and the disease may relapse again and again. Then the patients may wonder: is IgA Nephropathy curable? From the above mentioned aspects, we can see that only when the root cause, that is the damaged renal cells are well-treated can IgA Nephropathy be cured. To control the disease and stop it from deteriorating, we should focus on repairing of the impaired renal functions.
It has been proved that western medicines cannot radically solve the problem of preventing IgA Nephropathy from developing into Renal Failure. But you should not give up treating the disease just because of this. When you have adopted the right method, you can have a satisfactory curative effect. Let’s change our way of thinking: if western medicines can’t solve the problem, what about Chinese medicine?
Traditional Chinese medicine has a long developing history and it is the essence of thousands of years’ treating practice. In most people’s eyes, traditional Chinese medicine is just herbs which are to be decocted into herbal fluid and has a bitter taste. This makes may people unwilling to take Chinese medicine. In fact, there are many other treating methods by Chinese medicine such as external application, Chinese herb bath, acupuncture, etc. these can also be used in treatig kidney diseases.
In Shijiazhuang Kidney Disease Hospital, we have Micro-Chinese Medicine Osmotherapy which is just a creative way of treating kidney diseases. By micro-shattering of the herbs and permeating them into the renal region focus directly through external application and with the help of permeating equipments, this therapy can effectively treat kidney diseases without any painful experience to the patients. Moreover, by four functions of expanding blood vessel, anti-inflammation, anti-coagulation and degradation of extracellular matrix, it can effectively block the renal fibrosis and repair the damaged intrinsic cells, thus recovering the renal functions, which is just what western medicines cannot achieve. In this way, Micro-Chinese Medicine Osmotherapy has great advantage over western medicines in treating kidney diseases.
IgA Nephropathy, a kind of primary glomerulopathy, is characterized by deposition of IgA in mesangial area and accounts for 20%~40% of primary glomerulopathy. Hematuria is the most typical symptom of IgA Nephropathy and there can also be other symptoms such as proteinuria and high blood pressure. Although IgA Nephropathy is not so well-known as Nephritis or Uremia, it is a rather common kidney disease and is one of the main causes of Renal Failure. Therefore, patients with IgA Nephropathy should take measures earlier to prevent their disease from deteriorating.
Clinically, there are various pathological types of IgA Nephropathy such as mesangial proliferative IgA Nephropathy, focal proliferative IgA Nephropathy and proliferative sclerosing IgA Nephropathy. No matter what kind of IgA Nephropathy, the prognosis will be influenced by three aspects: serum creatinine, blood pressure and 24h urine protein quantitation.
Generally, when one is diagnosed IgA Nephrpathy, the doctor will use hormone, cytotoxic drugs or immunosuppressant, but the effects are not so satisfactory and the disease may relapse again and again. Then the patients may wonder: is IgA Nephropathy curable? From the above mentioned aspects, we can see that only when the root cause, that is the damaged renal cells are well-treated can IgA Nephropathy be cured. To control the disease and stop it from deteriorating, we should focus on repairing of the impaired renal functions.
It has been proved that western medicines cannot radically solve the problem of preventing IgA Nephropathy from developing into Renal Failure. But you should not give up treating the disease just because of this. When you have adopted the right method, you can have a satisfactory curative effect. Let’s change our way of thinking: if western medicines can’t solve the problem, what about Chinese medicine?
Traditional Chinese medicine has a long developing history and it is the essence of thousands of years’ treating practice. In most people’s eyes, traditional Chinese medicine is just herbs which are to be decocted into herbal fluid and has a bitter taste. This makes may people unwilling to take Chinese medicine. In fact, there are many other treating methods by Chinese medicine such as external application, Chinese herb bath, acupuncture, etc. these can also be used in treatig kidney diseases.
In Shijiazhuang Kidney Disease Hospital, we have Micro-Chinese Medicine Osmotherapy which is just a creative way of treating kidney diseases. By micro-shattering of the herbs and permeating them into the renal region focus directly through external application and with the help of permeating equipments, this therapy can effectively treat kidney diseases without any painful experience to the patients. Moreover, by four functions of expanding blood vessel, anti-inflammation, anti-coagulation and degradation of extracellular matrix, it can effectively block the renal fibrosis and repair the damaged intrinsic cells, thus recovering the renal functions, which is just what western medicines cannot achieve. In this way, Micro-Chinese Medicine Osmotherapy has great advantage over western medicines in treating kidney diseases.
2011年10月6日星期四
Complications of Hypertensive Nephropathy
1. Renal arteriosclerosis and Renal Failure
Hypertension has a close relation with kidneys. On one hand, Hypertension can cause kidney lesions; on the other hand, the kidney lesions can aggravate Hypertension. Hypertension and kidney lesions influence each other, thus forming a vicious circle. In addition, rapidly progressive Hypertension can lead to malignant renal arteriosclerosis, which will develop into Renal Failure quickly.
2. Cerebrovascular Accident
Cerebrovascular Accident is also known as stroke. It is serious, and its fatality rate is high. Even if it will not cause death, it will lead to disability in most cases. For patients with Hypertension, the higher the blood pressure is, the higher the incidence of stroke is. If patients have dizziness, headache, nausea, fatigue and other symptoms caused by anger, sudden accident, strenuous exercise and other incentives, the occurrence of stroke should be highly suspected, and the patients had better be taken to the hospitals immediately.
3. Coronary Heart Disease
The changes of the blood pressure can cause the imbalance of oxygen supply and oxygen demand of the myocardium. When patients with Hypertension have Left Ventricular Hypertrophy, it means Hypertensive Heart Disease occurs, which will finally lead to Heart Failure.
Hypertension has a close relation with kidneys. On one hand, Hypertension can cause kidney lesions; on the other hand, the kidney lesions can aggravate Hypertension. Hypertension and kidney lesions influence each other, thus forming a vicious circle. In addition, rapidly progressive Hypertension can lead to malignant renal arteriosclerosis, which will develop into Renal Failure quickly.
2. Cerebrovascular Accident
Cerebrovascular Accident is also known as stroke. It is serious, and its fatality rate is high. Even if it will not cause death, it will lead to disability in most cases. For patients with Hypertension, the higher the blood pressure is, the higher the incidence of stroke is. If patients have dizziness, headache, nausea, fatigue and other symptoms caused by anger, sudden accident, strenuous exercise and other incentives, the occurrence of stroke should be highly suspected, and the patients had better be taken to the hospitals immediately.
3. Coronary Heart Disease
The changes of the blood pressure can cause the imbalance of oxygen supply and oxygen demand of the myocardium. When patients with Hypertension have Left Ventricular Hypertrophy, it means Hypertensive Heart Disease occurs, which will finally lead to Heart Failure.
2011年10月5日星期三
Weakness and Development of Traditional Chinese Medicine
1. The strength of Traditional Chinese Medicine
Compared with Western Medicine, which is mainly aimed at managing the symptoms, Traditional Chinese Medicine focuses on why the body is not functioning properly and attempts to use individualized organic herbal formula to rejuvenate and restore the body to its natural state. That is to say, Traditional Chinese Medicine is aimed at the root cause of diseases.
However, with the development of science, the weakness of Traditional Chinese Medicine is becoming increasingly prominent. And here we will mainly discuss the weakness and development of Traditional Chinese Medicine in treating Nephrotic Syndrome.
2. The weakness of Traditional Chinese Medicine in treating Nephrotic Syndrome
In treating Nephrotic Syndrome, the therapeutic effect of Traditional Chinese Medicine is always not satisfying. Though it can treat this from the root, it may cause side effects in the long term and it will take a long time. And the specific performance are as follows:
※ The active ingredients of Traditional Chinese Medicine can not be fully released by boiling medicine.
※ taking the oral Chinese herbal soup for a long time may cause the following side effects:
a. Taking the Chinese herbal soup for a long term will stimulate the gastrointestinal tract and consume large amounts of gastric juice, thus causing nausea, vomit, poor appetite and other discomforts.
b. When the effective medicine entrys our human body, as the particles of the medicine are too large, a significant proportion of the medicines will be engulfed by the phagocytes in our body, thus the medicines can not be used fully.
c. The biological activity of the Traditional Chinese Medicine is low. The Traditional Chinese Medicine is only aimed at the kidneys, but not the kidney lesions more accurately. The drug concentration at the focal areas is almost the same with that at other healthy tissues. Therefore, it is a waste of the medicines.
3. The development of Traditional Chinese Medicine in treating Nephrotic Syndrome
Aiming at the weakness of Traditional Chinese Medicine in treating Nephrotic Syndrome, we have developed a new therapy. By this new treatment, the effective medicines are superfinely shattered and are permeated into our body by external application. And the effective medicines can directly act on the kidney lesions, thus treating Nephrotic Syndrome from the root. According to the characteristics of this therapy, it is named Micro-Chinese Medicine Osmotherapy.
Compared with Western Medicine, which is mainly aimed at managing the symptoms, Traditional Chinese Medicine focuses on why the body is not functioning properly and attempts to use individualized organic herbal formula to rejuvenate and restore the body to its natural state. That is to say, Traditional Chinese Medicine is aimed at the root cause of diseases.
However, with the development of science, the weakness of Traditional Chinese Medicine is becoming increasingly prominent. And here we will mainly discuss the weakness and development of Traditional Chinese Medicine in treating Nephrotic Syndrome.
2. The weakness of Traditional Chinese Medicine in treating Nephrotic Syndrome
In treating Nephrotic Syndrome, the therapeutic effect of Traditional Chinese Medicine is always not satisfying. Though it can treat this from the root, it may cause side effects in the long term and it will take a long time. And the specific performance are as follows:
※ The active ingredients of Traditional Chinese Medicine can not be fully released by boiling medicine.
※ taking the oral Chinese herbal soup for a long time may cause the following side effects:
a. Taking the Chinese herbal soup for a long term will stimulate the gastrointestinal tract and consume large amounts of gastric juice, thus causing nausea, vomit, poor appetite and other discomforts.
b. When the effective medicine entrys our human body, as the particles of the medicine are too large, a significant proportion of the medicines will be engulfed by the phagocytes in our body, thus the medicines can not be used fully.
c. The biological activity of the Traditional Chinese Medicine is low. The Traditional Chinese Medicine is only aimed at the kidneys, but not the kidney lesions more accurately. The drug concentration at the focal areas is almost the same with that at other healthy tissues. Therefore, it is a waste of the medicines.
3. The development of Traditional Chinese Medicine in treating Nephrotic Syndrome
Aiming at the weakness of Traditional Chinese Medicine in treating Nephrotic Syndrome, we have developed a new therapy. By this new treatment, the effective medicines are superfinely shattered and are permeated into our body by external application. And the effective medicines can directly act on the kidney lesions, thus treating Nephrotic Syndrome from the root. According to the characteristics of this therapy, it is named Micro-Chinese Medicine Osmotherapy.
Will Nephrotic Syndrome Develop into Uremia
When people develop Nephrotic Syndrome, most of them would want to know whether this disease will develop into Uremia one day.
Before giving a definite answer, we should firstly know that Nephrotic Syndrome is not an independent disease, but a set of signs or symptoms of the glomerular disease, typically showing large amounts of proteinuria, edema, hyperlipidemia and hypoproteinemia. Therefore, Nephrotic Syndrome will not necessarily develop into Uremia, for Nephrotic Syndrome of different pathological types has different prognosis. That is to say, if patients have not received effective treatment, or if they suffered from this disease repeatedly, then, Nephrotic Syndrome will develop slowly and finally develop into Uremia.
2. Since we have received treatment, why does this disease still develop?
This is because the root cause of Nephrotic Syndrome has not been removed.
When our healthy nephron are damaged, we also lose some of the renal functions gradually. And with the worsening of our condition, the damaged nephron will also progress to necrosis, and this pathological damage process is named as renal fibrosis. When the renal fibrosis progress to its end stage, then Uremia occurs.
In treating Nephrotic Syndrome, if the treatment is not aimed at effectively blocking the renal fibrosis, even though the patients' condition can turn better by the treatment of hormones, cyclophosphamide and other medicines, it is just temporal, and this disease is still easy to relapse. The reason is that the Western Medicine only has the anti-inflammatory effect, and it can not treat this disease from the root. Therefore, patients still have the chance to suffer from Uremia.
3. Since there is a chance for Nephrotic Syndrome developing into Uremia, what treatment can we expect?
Absolutely, if we want to refuse this "extremely unpleasant invitation" of suffering from Uremia, an effective and fundamental treatment is necessary. In turn, this disease should be treated from the root cause.
Before giving a definite answer, we should firstly know that Nephrotic Syndrome is not an independent disease, but a set of signs or symptoms of the glomerular disease, typically showing large amounts of proteinuria, edema, hyperlipidemia and hypoproteinemia. Therefore, Nephrotic Syndrome will not necessarily develop into Uremia, for Nephrotic Syndrome of different pathological types has different prognosis. That is to say, if patients have not received effective treatment, or if they suffered from this disease repeatedly, then, Nephrotic Syndrome will develop slowly and finally develop into Uremia.
2. Since we have received treatment, why does this disease still develop?
This is because the root cause of Nephrotic Syndrome has not been removed.
When our healthy nephron are damaged, we also lose some of the renal functions gradually. And with the worsening of our condition, the damaged nephron will also progress to necrosis, and this pathological damage process is named as renal fibrosis. When the renal fibrosis progress to its end stage, then Uremia occurs.
In treating Nephrotic Syndrome, if the treatment is not aimed at effectively blocking the renal fibrosis, even though the patients' condition can turn better by the treatment of hormones, cyclophosphamide and other medicines, it is just temporal, and this disease is still easy to relapse. The reason is that the Western Medicine only has the anti-inflammatory effect, and it can not treat this disease from the root. Therefore, patients still have the chance to suffer from Uremia.
3. Since there is a chance for Nephrotic Syndrome developing into Uremia, what treatment can we expect?
Absolutely, if we want to refuse this "extremely unpleasant invitation" of suffering from Uremia, an effective and fundamental treatment is necessary. In turn, this disease should be treated from the root cause.
2011年10月4日星期二
Can Patients with IgA Nephropathy Adopt Chinese Herb Bath Therapy?
First, let’s begin with the basic knowledge of IgA Nephropathy.
IgA Nephropathy is a group of chronic glomerulopathy caused by various factors and with the same immunopathological features. It is clinically manifested as gross hematuria or microscopic hematuria in about 40%~50% of the patients and microscopic hematuria accompanied with proteinuria in 35%~40% of the patients. The rest have manifestations of Nephrotic Syndrome and Renal Failure. The etiological factors of IgA Nephropathy are not very clear yet and it is generally believed that IgA Nephropathy is caused by deposition of immune complex.
Then what is IgA Nephropathy in traditional Chinese medicine?
The pathogenesis of IgA Nephropathy in view of traditional Chinese Medicine can be concluded as follows:
I. External attack of wind and heat. The combined attack of wind and heat will retain in the lungs and pass down to the bladder, causing ureteric damage and lower retention of heat in lower abdomen, which will then lead to the external symptoms of swelling (or edema) and hematuria.
II. Deficiency of liver-yin and kidney-yin. This is caused by deficiency of body-yin or excessive trouble and work. Yin asthenia can cause interior heat, which will then impair the renal collaterals and lead to urine blood.
III. Deficiency of spleen-qi and kidney-qi. This can be caused by deficiency of body-qi or overwork damaging the spleen and the kidneys. Failure of spleen to up transfuse the essence of water and grain and failure of kidneys to store essence will result in proteinuria; qi dysfunction in blood control will lead to hematuria.
In short, IgA Nephropathy is manifested principally as deficiency of yin or qi and secondarily as wind, damp-heat and blood stasis. Deficiency of yin is usually accompanied with damp-heat and deficiency of qi with blood stasis.
Thirdly, how does Chinese Herb Bath Therapy take effect?
Micro-Chinese Medicine bath therapy is one of the characteristic therapies of traditional Chinese medicine external treatment. Based on the concept of viewing the body as a whole in traditional Chinese medical science, this therapy makes the bath fluid through a complex procedure including choosing the appropriate Chinese herbal medicine and processing them in guidance of a series of principles like strengthening the body resistance, eliminating pathogen and blood stasis, removing body wastes and detoxication. Human body takes zang-fu (viscera) as its center and jing-luo (meridian, veins and arteries) as the connection, making it a whole including both the internal organs and the external limbs and skeletons as well as striae (of the skin, muscle and viscus). During the process of the herb bath, the medicine will act on the muscular striae and its nature, entering into human body through the acupoints, will flow in jing-luo and reach the internal organs, thus playing its role of promoting qi and blood circulation and regulating yin and yang from the external to the internal of the body.
To explain more specifically, hot steam of the herb bath will fumigate the skin of the patients all over the body, causing them to sweat, which is beneficial for eliminating edema and speeding the excretion of pathological products like blood stasis and toxins. In this way, level of toxic substances in the blood like creatinine and urea nitrogen will be lowered and renal functions and clinical symptoms will be improved, strengthening the organic immune competence.
Finally, we can draw the conclusion.
Therefore, Chinese Herb Bath Therapy is applicable for patients with IgA Nephropathy. On the one hand, it can effectively eliminate the toxins in their body; on the other hand, it will bring the patients a comfortable feeling both physically and mentally instead of painful experience as in some western medical treatments.
IgA Nephropathy is a group of chronic glomerulopathy caused by various factors and with the same immunopathological features. It is clinically manifested as gross hematuria or microscopic hematuria in about 40%~50% of the patients and microscopic hematuria accompanied with proteinuria in 35%~40% of the patients. The rest have manifestations of Nephrotic Syndrome and Renal Failure. The etiological factors of IgA Nephropathy are not very clear yet and it is generally believed that IgA Nephropathy is caused by deposition of immune complex.
Then what is IgA Nephropathy in traditional Chinese medicine?
The pathogenesis of IgA Nephropathy in view of traditional Chinese Medicine can be concluded as follows:
I. External attack of wind and heat. The combined attack of wind and heat will retain in the lungs and pass down to the bladder, causing ureteric damage and lower retention of heat in lower abdomen, which will then lead to the external symptoms of swelling (or edema) and hematuria.
II. Deficiency of liver-yin and kidney-yin. This is caused by deficiency of body-yin or excessive trouble and work. Yin asthenia can cause interior heat, which will then impair the renal collaterals and lead to urine blood.
III. Deficiency of spleen-qi and kidney-qi. This can be caused by deficiency of body-qi or overwork damaging the spleen and the kidneys. Failure of spleen to up transfuse the essence of water and grain and failure of kidneys to store essence will result in proteinuria; qi dysfunction in blood control will lead to hematuria.
In short, IgA Nephropathy is manifested principally as deficiency of yin or qi and secondarily as wind, damp-heat and blood stasis. Deficiency of yin is usually accompanied with damp-heat and deficiency of qi with blood stasis.
Thirdly, how does Chinese Herb Bath Therapy take effect?
Micro-Chinese Medicine bath therapy is one of the characteristic therapies of traditional Chinese medicine external treatment. Based on the concept of viewing the body as a whole in traditional Chinese medical science, this therapy makes the bath fluid through a complex procedure including choosing the appropriate Chinese herbal medicine and processing them in guidance of a series of principles like strengthening the body resistance, eliminating pathogen and blood stasis, removing body wastes and detoxication. Human body takes zang-fu (viscera) as its center and jing-luo (meridian, veins and arteries) as the connection, making it a whole including both the internal organs and the external limbs and skeletons as well as striae (of the skin, muscle and viscus). During the process of the herb bath, the medicine will act on the muscular striae and its nature, entering into human body through the acupoints, will flow in jing-luo and reach the internal organs, thus playing its role of promoting qi and blood circulation and regulating yin and yang from the external to the internal of the body.
To explain more specifically, hot steam of the herb bath will fumigate the skin of the patients all over the body, causing them to sweat, which is beneficial for eliminating edema and speeding the excretion of pathological products like blood stasis and toxins. In this way, level of toxic substances in the blood like creatinine and urea nitrogen will be lowered and renal functions and clinical symptoms will be improved, strengthening the organic immune competence.
Finally, we can draw the conclusion.
Therefore, Chinese Herb Bath Therapy is applicable for patients with IgA Nephropathy. On the one hand, it can effectively eliminate the toxins in their body; on the other hand, it will bring the patients a comfortable feeling both physically and mentally instead of painful experience as in some western medical treatments.
Treating Nephrotic Syndrome without Using Hormone Therapy?
I. How to regard hormone therapy in treating Nephrotic Syndrome?
We all know that hormone therapy is commonly used in treating kidney diseases including Nephrotic Syndrome. The reason is that hormone does have the effect of controlling the disease in a short time. However, many patients with kidney disease will turn pale at the mention of hormone. The reason lies in its side effects and its only curing the symptoms instead of the disease which will cause relapse of the disease once and again. Therefore, we shouldn’t arbitrarily judge hormone as good or bad. Moreover, we should use it carefully, such as avoiding stopping using it suddenly; otherwise, it will easily cause many side effects.
II. To make out whether we can treat NS without hormone, we should also know the pathogenesis of NS and how hormone takes effect in treating this disease.
Nephrotic Syndrome is a group of glomerulopathy that has similar pathological changes and clinical manifestations. The main changes are strengthened permeability of the glomerular membrane and decrease of GFR (Glomerular Filtration Rate). The typical manifestations include massive proteinuria, Hypoproteinemia, severe edema and Hyperlipemia.
Then how does hormone take effect in treating NS? Hormone has the function of inhibiting immunocytes and organic immunoreaction, so it can reduce damage of the renal intrinsic cells by immune complex. At the same time, it can protect intercellular matrix by balancing generation and degradation of polysaccharide. So hormone can effectively control the progress of the disease, especially the acute and active stage of NS.
Different pathological types of primary Nephrotic Syndrome should be treated with different application method of hormone, but the common adverse effect of it should be paid attention to: central obesity, high blood pressure, osteoporosis; digestive tract symptoms like nausea, vomiting and stress ulcer; spiritual symptoms like insomnia and excitation.
III. New therapy of treating Nephrotic Syndrome—significant effect of Micro-Chinese Medicine
Here, we can see that it is not easy to get rid of hormone completely. But don’t get discouraged, we have an effective way of avoid the side effects of hormone to a large extent—to combine hormone therapy with traditional Chinese medicine treatment, which has great power to reduce the side effects of hormone. Moreover, traditional Chinese medicine also has good curative effect in treating NS.
We all know that hormone therapy is commonly used in treating kidney diseases including Nephrotic Syndrome. The reason is that hormone does have the effect of controlling the disease in a short time. However, many patients with kidney disease will turn pale at the mention of hormone. The reason lies in its side effects and its only curing the symptoms instead of the disease which will cause relapse of the disease once and again. Therefore, we shouldn’t arbitrarily judge hormone as good or bad. Moreover, we should use it carefully, such as avoiding stopping using it suddenly; otherwise, it will easily cause many side effects.
II. To make out whether we can treat NS without hormone, we should also know the pathogenesis of NS and how hormone takes effect in treating this disease.
Nephrotic Syndrome is a group of glomerulopathy that has similar pathological changes and clinical manifestations. The main changes are strengthened permeability of the glomerular membrane and decrease of GFR (Glomerular Filtration Rate). The typical manifestations include massive proteinuria, Hypoproteinemia, severe edema and Hyperlipemia.
Then how does hormone take effect in treating NS? Hormone has the function of inhibiting immunocytes and organic immunoreaction, so it can reduce damage of the renal intrinsic cells by immune complex. At the same time, it can protect intercellular matrix by balancing generation and degradation of polysaccharide. So hormone can effectively control the progress of the disease, especially the acute and active stage of NS.
Different pathological types of primary Nephrotic Syndrome should be treated with different application method of hormone, but the common adverse effect of it should be paid attention to: central obesity, high blood pressure, osteoporosis; digestive tract symptoms like nausea, vomiting and stress ulcer; spiritual symptoms like insomnia and excitation.
III. New therapy of treating Nephrotic Syndrome—significant effect of Micro-Chinese Medicine
Here, we can see that it is not easy to get rid of hormone completely. But don’t get discouraged, we have an effective way of avoid the side effects of hormone to a large extent—to combine hormone therapy with traditional Chinese medicine treatment, which has great power to reduce the side effects of hormone. Moreover, traditional Chinese medicine also has good curative effect in treating NS.
2011年10月3日星期一
The Best Treatment for IgA Nephropathy
IgA Nephropathy, a kind of primary glomerulopathy, is characterized by deposition of IgA in mesangial area and accounts for 20%~40% of primary glomerulopathy. Hematuria is the most typical symptom of IgA Nephropathy and there can also be other symptoms such as proteinuria and high blood pressure. Although IgA Nephropathy is not so well-known as Nephritis or Uremia, it is a rather common kidney disease and is one of the main causes of Renal Failure. Therefore, patients with IgA Nephropathy should take measures earlier to prevent their disease from deteriorating.
Clinically, there are various pathological types of IgA Nephropathy such as mesangial proliferative IgA Nephropathy, focal proliferative IgA Nephropathy and proliferative sclerosing IgA Nephropathy. No matter what kind of IgA Nephropathy, the prognosis will be influenced by three aspects: serum creatinine, blood pressure and 24h urine protein quantitation.
Generally, when one is diagnosed IgA Nephrpathy, the doctor will use hormone, cytotoxic drugs or immunosuppressant, but the effects are not so satisfactory and the disease may relapse again and again. Then the patients may wonder: is IgA Nephropathy curable? From the above mentioned aspects, we can see that only when the root cause, that is the damaged renal cells are well-treated can IgA Nephropathy be cured. To control the disease and stop it from deteriorating, we should focus on repairing of the impaired renal functions.
It has been proved that western medicines cannot radically solve the problem of preventing IgA Nephropathy from developing into Renal Failure. But you should not give up treating the disease just because of this. When you have adopted the right method, you can have a satisfactory curative effect. Let’s change our way of thinking: if western medicines can’t solve the problem, what about Chinese medicine?
Traditional Chinese medicine has a long developing history and it is the essence of thousands of years’ treating practice. In most people’s eyes, traditional Chinese medicine is just herbs which are to be decocted into herbal fluid and has a bitter taste. This makes may people unwilling to take Chinese medicine. In fact, there are many other treating methods by Chinese medicine such as external application, Chinese herb bath, acupuncture, etc. these can also be used in treatig kidney diseases.
Clinically, there are various pathological types of IgA Nephropathy such as mesangial proliferative IgA Nephropathy, focal proliferative IgA Nephropathy and proliferative sclerosing IgA Nephropathy. No matter what kind of IgA Nephropathy, the prognosis will be influenced by three aspects: serum creatinine, blood pressure and 24h urine protein quantitation.
Generally, when one is diagnosed IgA Nephrpathy, the doctor will use hormone, cytotoxic drugs or immunosuppressant, but the effects are not so satisfactory and the disease may relapse again and again. Then the patients may wonder: is IgA Nephropathy curable? From the above mentioned aspects, we can see that only when the root cause, that is the damaged renal cells are well-treated can IgA Nephropathy be cured. To control the disease and stop it from deteriorating, we should focus on repairing of the impaired renal functions.
It has been proved that western medicines cannot radically solve the problem of preventing IgA Nephropathy from developing into Renal Failure. But you should not give up treating the disease just because of this. When you have adopted the right method, you can have a satisfactory curative effect. Let’s change our way of thinking: if western medicines can’t solve the problem, what about Chinese medicine?
Traditional Chinese medicine has a long developing history and it is the essence of thousands of years’ treating practice. In most people’s eyes, traditional Chinese medicine is just herbs which are to be decocted into herbal fluid and has a bitter taste. This makes may people unwilling to take Chinese medicine. In fact, there are many other treating methods by Chinese medicine such as external application, Chinese herb bath, acupuncture, etc. these can also be used in treatig kidney diseases.
How to Treat Focal Proliferative Sclerosing IgA Nephropathy?
FPS IgA Nephropathy is one of the pathological types of IgA Nephropathy. In specific, the kidneys have been damaged parenchymatously, i.e. some of the glomerular intrinsic cells are damaged. There will be abnormal protein and red blood cells in urine analysis which is caused by structural and functional changes of the glomerular filtration membrane and its abnormal filtration and interception functions.
As is known to all, treatment of kidney disease is rather complicated. At present, there is no specific effective treatment of Focal Proliferative Sclerosing IgA Nephropathy in western medicine. Pure application of western medicines such as hormone, Tripterygium wilfordii and Cyclophosphamide in anti-inflammatory treatments cannot change the renal state of ischemia and anoxia, so it cannot effectively repair the glomerular filtration membrane and recover its filtration function to a normal state. Therefore, these medicines are just treating the symptoms of proteinuria and occult blood by transiently inhibiting the generation of various receptors and controlling the damage and progress of the inflammatory reaction for a short time. But they cannot achieve the key point of repairing the damaged renal intrinsic cells, so even though the symptoms may disappear after using these medicines, the root cause is still unchanged and deposition of immune complex will reoccur and cause proteinuria and occult blood. This is exactly the reason why the disease is easy to recur by western medicine treatment.
Then what’s the correct treating method?
Treatment of this disease should vary from the patients’ physical condition, living habits, environmental factors and economic conditions as well as their recognition of this disease. It should be particularly emphasized that patients with unobvious symptoms and those who have had this disease for long shouldn’t be absent of mind and only care about whether urine routine has turned better. They should pay much attention to pathological changes of the renal parenchyma. Examinations such as isotope nephrogram and effective plasma flow of both kidneys are recommended, which are as important as general examinations.
Traditional Chinese Medicine can effectively treat renal functional damage in this disease and unlike hormone treatment, it doesn’t have any side effect. Then how can Chinese medicine treat this disease?
By its function of anti-inflammation, anti-allergy and anti-fibrosis of the glomeruli, traditional Chinese medicine can effectively change the condition of glomerular proliferation and effusion. It can gradually recover the renal functions by promoting fibrinolysis, reducing the agglomeration of the blood platelet and increasing GFR (Glomerular Filtration Rate). Through improving the permeability of the glomerular capillaries and increasing renal blood flow, Chinese medicine can recover the slightly or moderately damaged renal functions completely and partly recover the severely damaged renal functions. In addition, it can remit the renal atrophy to a certain extent.
Therefore, effective treatment of FPS IgA Nephropathy should be a combination of western medicine and Micro-Chinese Medicine Osmotherapy, with the former targeted at the anti-inflammatory treatment and the latter giving the radical treatment by reversing and repairing the damaged renal intrinsic cells, eliminating the excessive immune complex and at the same time providing the nutrition needed. By adopting these two methods, we can achieve a simultaneous treatment of both the symptoms and the essential disease. When the renal intrinsic cells are repaired, the inflammatory cells are inactivated and urine protein and occult blood have recovered to a normal range, then FPS IgA Nephropathy has achieved a systematic and standard treatment.
As is known to all, treatment of kidney disease is rather complicated. At present, there is no specific effective treatment of Focal Proliferative Sclerosing IgA Nephropathy in western medicine. Pure application of western medicines such as hormone, Tripterygium wilfordii and Cyclophosphamide in anti-inflammatory treatments cannot change the renal state of ischemia and anoxia, so it cannot effectively repair the glomerular filtration membrane and recover its filtration function to a normal state. Therefore, these medicines are just treating the symptoms of proteinuria and occult blood by transiently inhibiting the generation of various receptors and controlling the damage and progress of the inflammatory reaction for a short time. But they cannot achieve the key point of repairing the damaged renal intrinsic cells, so even though the symptoms may disappear after using these medicines, the root cause is still unchanged and deposition of immune complex will reoccur and cause proteinuria and occult blood. This is exactly the reason why the disease is easy to recur by western medicine treatment.
Then what’s the correct treating method?
Treatment of this disease should vary from the patients’ physical condition, living habits, environmental factors and economic conditions as well as their recognition of this disease. It should be particularly emphasized that patients with unobvious symptoms and those who have had this disease for long shouldn’t be absent of mind and only care about whether urine routine has turned better. They should pay much attention to pathological changes of the renal parenchyma. Examinations such as isotope nephrogram and effective plasma flow of both kidneys are recommended, which are as important as general examinations.
Traditional Chinese Medicine can effectively treat renal functional damage in this disease and unlike hormone treatment, it doesn’t have any side effect. Then how can Chinese medicine treat this disease?
By its function of anti-inflammation, anti-allergy and anti-fibrosis of the glomeruli, traditional Chinese medicine can effectively change the condition of glomerular proliferation and effusion. It can gradually recover the renal functions by promoting fibrinolysis, reducing the agglomeration of the blood platelet and increasing GFR (Glomerular Filtration Rate). Through improving the permeability of the glomerular capillaries and increasing renal blood flow, Chinese medicine can recover the slightly or moderately damaged renal functions completely and partly recover the severely damaged renal functions. In addition, it can remit the renal atrophy to a certain extent.
Therefore, effective treatment of FPS IgA Nephropathy should be a combination of western medicine and Micro-Chinese Medicine Osmotherapy, with the former targeted at the anti-inflammatory treatment and the latter giving the radical treatment by reversing and repairing the damaged renal intrinsic cells, eliminating the excessive immune complex and at the same time providing the nutrition needed. By adopting these two methods, we can achieve a simultaneous treatment of both the symptoms and the essential disease. When the renal intrinsic cells are repaired, the inflammatory cells are inactivated and urine protein and occult blood have recovered to a normal range, then FPS IgA Nephropathy has achieved a systematic and standard treatment.
2011年10月2日星期日
Systemic Lupus Erythematosus and Pregnancy
I. Effect of pregnancy on Systemic Lupus Erythematosus
For many women who have had Systemic Lupus Erythematosus, it has been troubled them if they want to have a baby, whether pregnancy will lead to the relapse of this disease.
Actually, there is still not a definite conclusion about it. However, through a series of studies, it is found that if this disease relapses in pregnancy, the patients' condition will not be more serious than that in normal cases. For those whose condition is mild, and has been controlled well, the recurrence rate is low. In a word, for women with Systemic Lupus Erythematosus, they should follow the guidance of their doctors during the whole process of pregnancy.
II. Permitted conditions of pregnancy for women with Systemic Lupus Erythematosus
It is indicated by studies that the active state of this disease is the important risk factor which can determine the relapse in pregnancy. In female patients with Lupus Nephritis, the recurrence rate in pregnancy is 7.4%~63%. The best time for female patients to get pregnant is 6~12 months after their condition has been controlled.
It is indicated by studies that in the following conditions, the adverse effect of pregnancy will decrease:
1. There are no serious heart or kidney involvement, abnormalities of the blood system, nervous system damage and liver damage
2. The remission period should last at least for one year
3. The renal function is normal, and the creatinine clearance rate should be maintained at 60%~80%
4. The maintenance dose of prednisone should be less than 15 mg/d, and immunosuppressant is not adopted
5. Those whose immune monitoring index increases are not appropriate to get pregnant, such as antinuclear antibody titers, anti-DNA antibodies, immunoglobulin quantitation, etc.
III. Suggestion for terminating and continuing the pregnancy
For those who are not appropriate for pregnancy, contraception measures are necessary. And if they get unplanned pregnancy, it should be terminated in the early stage, for more late the operation is done, more higher the risk will be.
For pregnant women with Systemic Lupus Erythematosus who do not receive treatment, large doses of glucocorticoid should be adopted to control the condition before receiving the abortion.
For those who can get pregnant, they should return visit their doctors regularly, and pay attention to monitor the complications of pregnancy. And the monitoring items include blood pressure, the condition of the unborn baby, blood and urine routine test, liver function, renal function and the aforementioned immune monitoring index. In addition, they should be hospitalized one month before the expected date of childbirth.
For many women who have had Systemic Lupus Erythematosus, it has been troubled them if they want to have a baby, whether pregnancy will lead to the relapse of this disease.
Actually, there is still not a definite conclusion about it. However, through a series of studies, it is found that if this disease relapses in pregnancy, the patients' condition will not be more serious than that in normal cases. For those whose condition is mild, and has been controlled well, the recurrence rate is low. In a word, for women with Systemic Lupus Erythematosus, they should follow the guidance of their doctors during the whole process of pregnancy.
II. Permitted conditions of pregnancy for women with Systemic Lupus Erythematosus
It is indicated by studies that the active state of this disease is the important risk factor which can determine the relapse in pregnancy. In female patients with Lupus Nephritis, the recurrence rate in pregnancy is 7.4%~63%. The best time for female patients to get pregnant is 6~12 months after their condition has been controlled.
It is indicated by studies that in the following conditions, the adverse effect of pregnancy will decrease:
1. There are no serious heart or kidney involvement, abnormalities of the blood system, nervous system damage and liver damage
2. The remission period should last at least for one year
3. The renal function is normal, and the creatinine clearance rate should be maintained at 60%~80%
4. The maintenance dose of prednisone should be less than 15 mg/d, and immunosuppressant is not adopted
5. Those whose immune monitoring index increases are not appropriate to get pregnant, such as antinuclear antibody titers, anti-DNA antibodies, immunoglobulin quantitation, etc.
III. Suggestion for terminating and continuing the pregnancy
For those who are not appropriate for pregnancy, contraception measures are necessary. And if they get unplanned pregnancy, it should be terminated in the early stage, for more late the operation is done, more higher the risk will be.
For pregnant women with Systemic Lupus Erythematosus who do not receive treatment, large doses of glucocorticoid should be adopted to control the condition before receiving the abortion.
For those who can get pregnant, they should return visit their doctors regularly, and pay attention to monitor the complications of pregnancy. And the monitoring items include blood pressure, the condition of the unborn baby, blood and urine routine test, liver function, renal function and the aforementioned immune monitoring index. In addition, they should be hospitalized one month before the expected date of childbirth.
2011年10月1日星期六
Will Nephrotic Syndrome Develop into Uremia
Will Nephrotic Syndrome Develop into Uremia? We should pay attention to what?
1. Will Nephrotic Syndrome develop into Uremia?
When people develop Nephrotic Syndrome, most of them would want to know whether this disease will develop into Uremia one day.
Before giving a definite answer, we should firstly know that Nephrotic Syndrome is not an independent disease, but a set of signs or symptoms of the glomerular disease, typically showing large amounts of proteinuria, edema, hyperlipidemia and hypoproteinemia. Therefore, Nephrotic Syndrome will not necessarily develop into Uremia, for Nephrotic Syndrome of different pathological types has different prognosis. That is to say, if patients have not received effective treatment, or if they suffered from this disease repeatedly, then, Nephrotic Syndrome will develop slowly and finally develop into Uremia.
2. Since we have received treatment, why does this disease still develop?
This is because the root cause of Nephrotic Syndrome has not been removed.
When our healthy nephron are damaged, we also lose some of the renal functions gradually. And with the worsening of our condition, the damaged nephron will also progress to necrosis, and this pathological damage process is named as renal fibrosis. When the renal fibrosis progress to its end stage, then Uremia occurs.
In treating Nephrotic Syndrome, if the treatment is not aimed at effectively blocking the renal fibrosis, even though the patients' condition can turn better by the treatment of hormones, cyclophosphamide and other medicines, it is just temporal, and this disease is still easy to relapse. The reason is that the Western Medicine only has the anti-inflammatory effect, and it can not treat this disease from the root. Therefore, patients still have the chance to suffer from Uremia.
3. Since there is a chance for Nephrotic Syndrome developing into Uremia, what treatment can we expect?
Absolutely, if we want to refuse this "extremely unpleasant invitation" of suffering from Uremia, an effective and fundamental treatment is necessary. In turn, this disease should be treated from the root cause.
Our characteristic treatment not only have the anti-inflammatory effect of Western Medicine, but also can supply nutrients for the kidneys, improve the condition of ischemia and hypoxia, and repair the damaged kidney tissues, thus rebuilding the renal function. And this treatment is named as Micro-Chinese Medicine Osmotherapy.
1. Will Nephrotic Syndrome develop into Uremia?
When people develop Nephrotic Syndrome, most of them would want to know whether this disease will develop into Uremia one day.
Before giving a definite answer, we should firstly know that Nephrotic Syndrome is not an independent disease, but a set of signs or symptoms of the glomerular disease, typically showing large amounts of proteinuria, edema, hyperlipidemia and hypoproteinemia. Therefore, Nephrotic Syndrome will not necessarily develop into Uremia, for Nephrotic Syndrome of different pathological types has different prognosis. That is to say, if patients have not received effective treatment, or if they suffered from this disease repeatedly, then, Nephrotic Syndrome will develop slowly and finally develop into Uremia.
2. Since we have received treatment, why does this disease still develop?
This is because the root cause of Nephrotic Syndrome has not been removed.
When our healthy nephron are damaged, we also lose some of the renal functions gradually. And with the worsening of our condition, the damaged nephron will also progress to necrosis, and this pathological damage process is named as renal fibrosis. When the renal fibrosis progress to its end stage, then Uremia occurs.
In treating Nephrotic Syndrome, if the treatment is not aimed at effectively blocking the renal fibrosis, even though the patients' condition can turn better by the treatment of hormones, cyclophosphamide and other medicines, it is just temporal, and this disease is still easy to relapse. The reason is that the Western Medicine only has the anti-inflammatory effect, and it can not treat this disease from the root. Therefore, patients still have the chance to suffer from Uremia.
3. Since there is a chance for Nephrotic Syndrome developing into Uremia, what treatment can we expect?
Absolutely, if we want to refuse this "extremely unpleasant invitation" of suffering from Uremia, an effective and fundamental treatment is necessary. In turn, this disease should be treated from the root cause.
Our characteristic treatment not only have the anti-inflammatory effect of Western Medicine, but also can supply nutrients for the kidneys, improve the condition of ischemia and hypoxia, and repair the damaged kidney tissues, thus rebuilding the renal function. And this treatment is named as Micro-Chinese Medicine Osmotherapy.
Dietary Notice for Purpura Nephritis
For patients with Purpura Nephritis, what dietary notice should they pay attention to?
1. You should immediately avoid contacting or using some foods, medicines, pollen or paint which can cause allergy, and the foods mainly are milk, crabs, shrimps, eggs and mutton, medicines mainly are sulfa, penicillin preparation, antipyretic analgesics and insulin.
2. The daily diet should be delicate, rich in nutrient and easy to be digested. Greasy food should be avoided. In addition, in order to avoid inducing or aggravating gastrointestinal bleeding, the following points should also be paid attention to:
· When we have a meal, we had better not eat too full, for it will increase the burden on our stomach and intestine
· We should eat more refined foods, and less coarse food grain and foods containing much crude fibre such as celery, rape, bamboo shoot and pineapple, for the latter will abrade the gastrointestinal mucosa, thus inducing or aggravating gastrointestinal bleeding
· Smoking, drinking and spicy foods should also be avoided
3. The appropriate daily intake of protein should be 1 g per kilogram of the body weight, for if the protein intake is too less, it will cause continued low level of plasma protein which will reduce our body resistance, thus causing infection easily; if the protein intake is too much, it will cause high filtration of the glomeruli which will promote glomerular sclerosis finally. In addition, we should mainly take high-quality protein foods such as eggs, lean meat and fresh milk.
4. A low-salt diet is appropriate for patients with Purpura Nephritis. Generally, the daily intake should be 1~3 grams, and for those who have serious edema, the daily intake should be no more than 0.5 grams.
5. For patients with Purpura Nephritis who do not have oliguria or edema, there is no limitation for the daily intake of water. And for those who has obvious edema, besides water in the meals, the daily intake of water should be 500~800 ml.
6. During the period of treatment, patients should have a good rest, and the sexual life should be decreased.
1. You should immediately avoid contacting or using some foods, medicines, pollen or paint which can cause allergy, and the foods mainly are milk, crabs, shrimps, eggs and mutton, medicines mainly are sulfa, penicillin preparation, antipyretic analgesics and insulin.
2. The daily diet should be delicate, rich in nutrient and easy to be digested. Greasy food should be avoided. In addition, in order to avoid inducing or aggravating gastrointestinal bleeding, the following points should also be paid attention to:
· When we have a meal, we had better not eat too full, for it will increase the burden on our stomach and intestine
· We should eat more refined foods, and less coarse food grain and foods containing much crude fibre such as celery, rape, bamboo shoot and pineapple, for the latter will abrade the gastrointestinal mucosa, thus inducing or aggravating gastrointestinal bleeding
· Smoking, drinking and spicy foods should also be avoided
3. The appropriate daily intake of protein should be 1 g per kilogram of the body weight, for if the protein intake is too less, it will cause continued low level of plasma protein which will reduce our body resistance, thus causing infection easily; if the protein intake is too much, it will cause high filtration of the glomeruli which will promote glomerular sclerosis finally. In addition, we should mainly take high-quality protein foods such as eggs, lean meat and fresh milk.
4. A low-salt diet is appropriate for patients with Purpura Nephritis. Generally, the daily intake should be 1~3 grams, and for those who have serious edema, the daily intake should be no more than 0.5 grams.
5. For patients with Purpura Nephritis who do not have oliguria or edema, there is no limitation for the daily intake of water. And for those who has obvious edema, besides water in the meals, the daily intake of water should be 500~800 ml.
6. During the period of treatment, patients should have a good rest, and the sexual life should be decreased.
Can Nephrotic Syndrome Be Cured with Hormone
Can Nephrotic Syndrome Be Cured with Hormone?Long-term use of hormone of great damage.
At present, Nephrotic Syndrome is mainly treated with hormone. And one of the most frequently asked questions by patients is "Can Nephrotic Syndrome be cured with hormone?". Before we announce the answer, let's have a clear knowing of the therapeutic effect of hormone first.
1. The therapeutic effect of hormone
The hormone therapy really has a good therapeutic effect: the anti-inflammatory effect of hormone is good. With hormones, the inflammatory response can be controlled in a short time, thus preventing further damages to the renal intrinsic cells. And for patients who are sensitive to hormones, the large amounts of proteinuria will disappear in a short time, and their urine protein will turn negative in several days or a month. Therefore, this therapy really relieves the patients' pain in a certain degree.
As hormone has a good therapeutic effect in treating Nephrotic Syndrome, then, does it means that Nephrotic Syndrome can be cured with hormone?
2. Can Nephrotic Syndrome be cured with hormone?
When the symptoms remit or disappear after the treatment, the dose of hormone will usually be decreased. And most patients would thought that they are going to be cured. However, after a long-term treatment, they only find that this disease begins to relapse again and again, and even worse, this disease will develop into End-Stage Kidney Disease in some patients. In a word, Nephrotic Syndrome can not be cured with hormone.
As the therapeutic effect of hormone is good, some patients would wonder why this disease cannot be cured by hormone therapy. Actually, as a kind of Western Medicine, hormone therapy is just a kind of symptomatic treatment. That is to say, in treating this disease, it is only aimed at the symptoms, but not the root—the damaged nephron. Though the urine protein has been decreased or has disappeared, the kidney lesions still exist, and when patients have colds or infections, this disease relapse. And every relapse will aggravate the pathological damages of the kidney, and finally lead to End-Stage Kidney Disease.
Therefore, hormone therapy is not the best option for patients with Nephrotic Syndrome. Now there is a new treatment which can treat Nephrotic Syndrome fundamentally. It uses Traditional Chinese Medicine without side effects, for the effective medicines are permeated into the kidney lesions by external application. In addition, this new treatment is aimed at repairing and rebuilding the renal function, thus treating this disease from the root. And this new treatment is named Micro-Chinese Medicine Osmotherapy in our hospital.
At present, Nephrotic Syndrome is mainly treated with hormone. And one of the most frequently asked questions by patients is "Can Nephrotic Syndrome be cured with hormone?". Before we announce the answer, let's have a clear knowing of the therapeutic effect of hormone first.
1. The therapeutic effect of hormone
The hormone therapy really has a good therapeutic effect: the anti-inflammatory effect of hormone is good. With hormones, the inflammatory response can be controlled in a short time, thus preventing further damages to the renal intrinsic cells. And for patients who are sensitive to hormones, the large amounts of proteinuria will disappear in a short time, and their urine protein will turn negative in several days or a month. Therefore, this therapy really relieves the patients' pain in a certain degree.
As hormone has a good therapeutic effect in treating Nephrotic Syndrome, then, does it means that Nephrotic Syndrome can be cured with hormone?
2. Can Nephrotic Syndrome be cured with hormone?
When the symptoms remit or disappear after the treatment, the dose of hormone will usually be decreased. And most patients would thought that they are going to be cured. However, after a long-term treatment, they only find that this disease begins to relapse again and again, and even worse, this disease will develop into End-Stage Kidney Disease in some patients. In a word, Nephrotic Syndrome can not be cured with hormone.
As the therapeutic effect of hormone is good, some patients would wonder why this disease cannot be cured by hormone therapy. Actually, as a kind of Western Medicine, hormone therapy is just a kind of symptomatic treatment. That is to say, in treating this disease, it is only aimed at the symptoms, but not the root—the damaged nephron. Though the urine protein has been decreased or has disappeared, the kidney lesions still exist, and when patients have colds or infections, this disease relapse. And every relapse will aggravate the pathological damages of the kidney, and finally lead to End-Stage Kidney Disease.
Therefore, hormone therapy is not the best option for patients with Nephrotic Syndrome. Now there is a new treatment which can treat Nephrotic Syndrome fundamentally. It uses Traditional Chinese Medicine without side effects, for the effective medicines are permeated into the kidney lesions by external application. In addition, this new treatment is aimed at repairing and rebuilding the renal function, thus treating this disease from the root. And this new treatment is named Micro-Chinese Medicine Osmotherapy in our hospital.
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