How to Treat Focal Proliferative Sclerosing IgA Nephropathy?

FPS IgA Nephropathy is one of the pathological types of IgA Nephropathy. In specific, the kidneys have been damaged parenchymatously, i.e. some of the glomerular intrinsic cells are damaged. There will be abnormal protein and red blood cells in urine analysis which is caused by structural and functional changes of the glomerular filtration membrane and its abnormal filtration and interception functions.
As is known to all, treatment of kidney disease is rather complicated. At present, there is no specific effective treatment of Focal Proliferative Sclerosing IgA Nephropathy in western medicine. Pure application of western medicines such as hormone, Tripterygium wilfordii and Cyclophosphamide in anti-inflammatory treatments cannot change the renal state of ischemia and anoxia, so it cannot effectively repair the glomerular filtration membrane and recover its filtration function to a normal state. Therefore, these medicines are just treating the symptoms of proteinuria and occult blood by transiently inhibiting the generation of various receptors and controlling the damage and progress of the inflammatory reaction for a short time. But they cannot achieve the key point of repairing the damaged renal intrinsic cells, so even though the symptoms may disappear after using these medicines, the root cause is still unchanged and deposition of immune complex will reoccur and cause proteinuria and occult blood. This is exactly the reason why the disease is easy to recur by western medicine treatment.
Then what’s the correct treating method?
Treatment of this disease should vary from the patients’ physical condition, living habits, environmental factors and economic conditions as well as their recognition of this disease. It should be particularly emphasized that patients with unobvious symptoms and those who have had this disease for long shouldn’t be absent of mind and only care about whether urine routine has turned better. They should pay much attention to pathological changes of the renal parenchyma. Examinations such as isotope nephrogram and effective plasma flow of both kidneys are recommended, which are as important as general examinations.
Traditional Chinese Medicine can effectively treat renal functional damage in this disease and unlike hormone treatment, it doesn’t have any side effect. Then how can Chinese medicine treat this disease?
By its function of anti-inflammation, anti-allergy and anti-fibrosis of the glomeruli, traditional Chinese medicine can effectively change the condition of glomerular proliferation and effusion. It can gradually recover the renal functions by promoting fibrinolysis, reducing the agglomeration of the blood platelet and increasing GFR (Glomerular Filtration Rate). Through improving the permeability of the glomerular capillaries and increasing renal blood flow, Chinese medicine can recover the slightly or moderately damaged renal functions completely and partly recover the severely damaged renal functions. In addition, it can remit the renal atrophy to a certain extent.
Therefore, effective treatment of FPS IgA Nephropathy should be a combination of western medicine and Micro-Chinese Medicine Osmotherapy, with the former targeted at the anti-inflammatory treatment and the latter giving the radical treatment by reversing and repairing the damaged renal intrinsic cells, eliminating the excessive immune complex and at the same time providing the nutrition needed. By adopting these two methods, we can achieve a simultaneous treatment of both the symptoms and the essential disease. When the renal intrinsic cells are repaired, the inflammatory cells are inactivated and urine protein and occult blood have recovered to a normal range, then FPS IgA Nephropathy has achieved a systematic and standard treatment.