What is the best treatment for IgA nephropathy? What is it
IgA Nephropathy, a kind of primary glomerulopathy, is characterized by deposition of IgA in mesangial area and accounts for 20%~40% of primary glomerulopathy. Hematuria is the most typical symptom of IgA Nephropathy and there can also be other symptoms such as proteinuria and high blood pressure. Although IgA Nephropathy is not so well-known as Nephritis or Uremia, it is a rather common kidney disease and is one of the main causes of Renal Failure. Therefore, patients with IgA Nephropathy should take measures earlier to prevent their disease from deteriorating.
Clinically, there are various pathological types of IgA Nephropathy such as mesangial proliferative IgA Nephropathy, focal proliferative IgA Nephropathy and proliferative sclerosing IgA Nephropathy. No matter what kind of IgA Nephropathy, the prognosis will be influenced by three aspects: serum creatinine, blood pressure and 24h urine protein quantitation.
Generally, when one is diagnosed IgA Nephrpathy, the doctor will use hormone, cytotoxic drugs or immunosuppressant, but the effects are not so satisfactory and the disease may relapse again and again. Then the patients may wonder: is IgA Nephropathy curable? From the above mentioned aspects, we can see that only when the root cause, that is the damaged renal cells are well-treated can IgA Nephropathy be cured. To control the disease and stop it from deteriorating, we should focus on repairing of the impaired renal functions.
It has been proved that western medicines cannot radically solve the problem of preventing IgA Nephropathy from developing into Renal Failure. But you should not give up treating the disease just because of this. When you have adopted the right method, you can have a satisfactory curative effect. Let’s change our way of thinking: if western medicines can’t solve the problem, what about Chinese medicine?
Traditional Chinese medicine has a long developing history and it is the essence of thousands of years’ treating practice. In most people’s eyes, traditional Chinese medicine is just herbs which are to be decocted into herbal fluid and has a bitter taste. This makes may people unwilling to take Chinese medicine. In fact, there are many other treating methods by Chinese medicine such as external application, Chinese herb bath, acupuncture, etc. these can also be used in treatig kidney diseases.
In Shijiazhuang Kidney Disease Hospital, we have Micro-Chinese Medicine Osmotherapy which is just a creative way of treating kidney diseases. By micro-shattering of the herbs and permeating them into the renal region focus directly through external application and with the help of permeating equipments, this therapy can effectively treat kidney diseases without any painful experience to the patients. Moreover, by four functions of expanding blood vessel, anti-inflammation, anti-coagulation and degradation of extracellular matrix, it can effectively block the renal fibrosis and repair the damaged intrinsic cells, thus recovering the renal functions, which is just what western medicines cannot achieve. In this way, Micro-Chinese Medicine Osmotherapy has great advantage over western medicines in treating kidney diseases.
2011年10月7日星期五
2011年10月4日星期二
Can Patients with IgA Nephropathy Adopt Chinese Herb Bath Therapy?
First, let’s begin with the basic knowledge of IgA Nephropathy.
IgA Nephropathy is a group of chronic glomerulopathy caused by various factors and with the same immunopathological features. It is clinically manifested as gross hematuria or microscopic hematuria in about 40%~50% of the patients and microscopic hematuria accompanied with proteinuria in 35%~40% of the patients. The rest have manifestations of Nephrotic Syndrome and Renal Failure. The etiological factors of IgA Nephropathy are not very clear yet and it is generally believed that IgA Nephropathy is caused by deposition of immune complex.
Then what is IgA Nephropathy in traditional Chinese medicine?
The pathogenesis of IgA Nephropathy in view of traditional Chinese Medicine can be concluded as follows:
I. External attack of wind and heat. The combined attack of wind and heat will retain in the lungs and pass down to the bladder, causing ureteric damage and lower retention of heat in lower abdomen, which will then lead to the external symptoms of swelling (or edema) and hematuria.
II. Deficiency of liver-yin and kidney-yin. This is caused by deficiency of body-yin or excessive trouble and work. Yin asthenia can cause interior heat, which will then impair the renal collaterals and lead to urine blood.
III. Deficiency of spleen-qi and kidney-qi. This can be caused by deficiency of body-qi or overwork damaging the spleen and the kidneys. Failure of spleen to up transfuse the essence of water and grain and failure of kidneys to store essence will result in proteinuria; qi dysfunction in blood control will lead to hematuria.
In short, IgA Nephropathy is manifested principally as deficiency of yin or qi and secondarily as wind, damp-heat and blood stasis. Deficiency of yin is usually accompanied with damp-heat and deficiency of qi with blood stasis.
Thirdly, how does Chinese Herb Bath Therapy take effect?
Micro-Chinese Medicine bath therapy is one of the characteristic therapies of traditional Chinese medicine external treatment. Based on the concept of viewing the body as a whole in traditional Chinese medical science, this therapy makes the bath fluid through a complex procedure including choosing the appropriate Chinese herbal medicine and processing them in guidance of a series of principles like strengthening the body resistance, eliminating pathogen and blood stasis, removing body wastes and detoxication. Human body takes zang-fu (viscera) as its center and jing-luo (meridian, veins and arteries) as the connection, making it a whole including both the internal organs and the external limbs and skeletons as well as striae (of the skin, muscle and viscus). During the process of the herb bath, the medicine will act on the muscular striae and its nature, entering into human body through the acupoints, will flow in jing-luo and reach the internal organs, thus playing its role of promoting qi and blood circulation and regulating yin and yang from the external to the internal of the body.
To explain more specifically, hot steam of the herb bath will fumigate the skin of the patients all over the body, causing them to sweat, which is beneficial for eliminating edema and speeding the excretion of pathological products like blood stasis and toxins. In this way, level of toxic substances in the blood like creatinine and urea nitrogen will be lowered and renal functions and clinical symptoms will be improved, strengthening the organic immune competence.
Finally, we can draw the conclusion.
Therefore, Chinese Herb Bath Therapy is applicable for patients with IgA Nephropathy. On the one hand, it can effectively eliminate the toxins in their body; on the other hand, it will bring the patients a comfortable feeling both physically and mentally instead of painful experience as in some western medical treatments.
IgA Nephropathy is a group of chronic glomerulopathy caused by various factors and with the same immunopathological features. It is clinically manifested as gross hematuria or microscopic hematuria in about 40%~50% of the patients and microscopic hematuria accompanied with proteinuria in 35%~40% of the patients. The rest have manifestations of Nephrotic Syndrome and Renal Failure. The etiological factors of IgA Nephropathy are not very clear yet and it is generally believed that IgA Nephropathy is caused by deposition of immune complex.
Then what is IgA Nephropathy in traditional Chinese medicine?
The pathogenesis of IgA Nephropathy in view of traditional Chinese Medicine can be concluded as follows:
I. External attack of wind and heat. The combined attack of wind and heat will retain in the lungs and pass down to the bladder, causing ureteric damage and lower retention of heat in lower abdomen, which will then lead to the external symptoms of swelling (or edema) and hematuria.
II. Deficiency of liver-yin and kidney-yin. This is caused by deficiency of body-yin or excessive trouble and work. Yin asthenia can cause interior heat, which will then impair the renal collaterals and lead to urine blood.
III. Deficiency of spleen-qi and kidney-qi. This can be caused by deficiency of body-qi or overwork damaging the spleen and the kidneys. Failure of spleen to up transfuse the essence of water and grain and failure of kidneys to store essence will result in proteinuria; qi dysfunction in blood control will lead to hematuria.
In short, IgA Nephropathy is manifested principally as deficiency of yin or qi and secondarily as wind, damp-heat and blood stasis. Deficiency of yin is usually accompanied with damp-heat and deficiency of qi with blood stasis.
Thirdly, how does Chinese Herb Bath Therapy take effect?
Micro-Chinese Medicine bath therapy is one of the characteristic therapies of traditional Chinese medicine external treatment. Based on the concept of viewing the body as a whole in traditional Chinese medical science, this therapy makes the bath fluid through a complex procedure including choosing the appropriate Chinese herbal medicine and processing them in guidance of a series of principles like strengthening the body resistance, eliminating pathogen and blood stasis, removing body wastes and detoxication. Human body takes zang-fu (viscera) as its center and jing-luo (meridian, veins and arteries) as the connection, making it a whole including both the internal organs and the external limbs and skeletons as well as striae (of the skin, muscle and viscus). During the process of the herb bath, the medicine will act on the muscular striae and its nature, entering into human body through the acupoints, will flow in jing-luo and reach the internal organs, thus playing its role of promoting qi and blood circulation and regulating yin and yang from the external to the internal of the body.
To explain more specifically, hot steam of the herb bath will fumigate the skin of the patients all over the body, causing them to sweat, which is beneficial for eliminating edema and speeding the excretion of pathological products like blood stasis and toxins. In this way, level of toxic substances in the blood like creatinine and urea nitrogen will be lowered and renal functions and clinical symptoms will be improved, strengthening the organic immune competence.
Finally, we can draw the conclusion.
Therefore, Chinese Herb Bath Therapy is applicable for patients with IgA Nephropathy. On the one hand, it can effectively eliminate the toxins in their body; on the other hand, it will bring the patients a comfortable feeling both physically and mentally instead of painful experience as in some western medical treatments.
2011年10月3日星期一
The Best Treatment for IgA Nephropathy
IgA Nephropathy, a kind of primary glomerulopathy, is characterized by deposition of IgA in mesangial area and accounts for 20%~40% of primary glomerulopathy. Hematuria is the most typical symptom of IgA Nephropathy and there can also be other symptoms such as proteinuria and high blood pressure. Although IgA Nephropathy is not so well-known as Nephritis or Uremia, it is a rather common kidney disease and is one of the main causes of Renal Failure. Therefore, patients with IgA Nephropathy should take measures earlier to prevent their disease from deteriorating.
Clinically, there are various pathological types of IgA Nephropathy such as mesangial proliferative IgA Nephropathy, focal proliferative IgA Nephropathy and proliferative sclerosing IgA Nephropathy. No matter what kind of IgA Nephropathy, the prognosis will be influenced by three aspects: serum creatinine, blood pressure and 24h urine protein quantitation.
Generally, when one is diagnosed IgA Nephrpathy, the doctor will use hormone, cytotoxic drugs or immunosuppressant, but the effects are not so satisfactory and the disease may relapse again and again. Then the patients may wonder: is IgA Nephropathy curable? From the above mentioned aspects, we can see that only when the root cause, that is the damaged renal cells are well-treated can IgA Nephropathy be cured. To control the disease and stop it from deteriorating, we should focus on repairing of the impaired renal functions.
It has been proved that western medicines cannot radically solve the problem of preventing IgA Nephropathy from developing into Renal Failure. But you should not give up treating the disease just because of this. When you have adopted the right method, you can have a satisfactory curative effect. Let’s change our way of thinking: if western medicines can’t solve the problem, what about Chinese medicine?
Traditional Chinese medicine has a long developing history and it is the essence of thousands of years’ treating practice. In most people’s eyes, traditional Chinese medicine is just herbs which are to be decocted into herbal fluid and has a bitter taste. This makes may people unwilling to take Chinese medicine. In fact, there are many other treating methods by Chinese medicine such as external application, Chinese herb bath, acupuncture, etc. these can also be used in treatig kidney diseases.
Clinically, there are various pathological types of IgA Nephropathy such as mesangial proliferative IgA Nephropathy, focal proliferative IgA Nephropathy and proliferative sclerosing IgA Nephropathy. No matter what kind of IgA Nephropathy, the prognosis will be influenced by three aspects: serum creatinine, blood pressure and 24h urine protein quantitation.
Generally, when one is diagnosed IgA Nephrpathy, the doctor will use hormone, cytotoxic drugs or immunosuppressant, but the effects are not so satisfactory and the disease may relapse again and again. Then the patients may wonder: is IgA Nephropathy curable? From the above mentioned aspects, we can see that only when the root cause, that is the damaged renal cells are well-treated can IgA Nephropathy be cured. To control the disease and stop it from deteriorating, we should focus on repairing of the impaired renal functions.
It has been proved that western medicines cannot radically solve the problem of preventing IgA Nephropathy from developing into Renal Failure. But you should not give up treating the disease just because of this. When you have adopted the right method, you can have a satisfactory curative effect. Let’s change our way of thinking: if western medicines can’t solve the problem, what about Chinese medicine?
Traditional Chinese medicine has a long developing history and it is the essence of thousands of years’ treating practice. In most people’s eyes, traditional Chinese medicine is just herbs which are to be decocted into herbal fluid and has a bitter taste. This makes may people unwilling to take Chinese medicine. In fact, there are many other treating methods by Chinese medicine such as external application, Chinese herb bath, acupuncture, etc. these can also be used in treatig kidney diseases.
How to Treat Focal Proliferative Sclerosing IgA Nephropathy?
FPS IgA Nephropathy is one of the pathological types of IgA Nephropathy. In specific, the kidneys have been damaged parenchymatously, i.e. some of the glomerular intrinsic cells are damaged. There will be abnormal protein and red blood cells in urine analysis which is caused by structural and functional changes of the glomerular filtration membrane and its abnormal filtration and interception functions.
As is known to all, treatment of kidney disease is rather complicated. At present, there is no specific effective treatment of Focal Proliferative Sclerosing IgA Nephropathy in western medicine. Pure application of western medicines such as hormone, Tripterygium wilfordii and Cyclophosphamide in anti-inflammatory treatments cannot change the renal state of ischemia and anoxia, so it cannot effectively repair the glomerular filtration membrane and recover its filtration function to a normal state. Therefore, these medicines are just treating the symptoms of proteinuria and occult blood by transiently inhibiting the generation of various receptors and controlling the damage and progress of the inflammatory reaction for a short time. But they cannot achieve the key point of repairing the damaged renal intrinsic cells, so even though the symptoms may disappear after using these medicines, the root cause is still unchanged and deposition of immune complex will reoccur and cause proteinuria and occult blood. This is exactly the reason why the disease is easy to recur by western medicine treatment.
Then what’s the correct treating method?
Treatment of this disease should vary from the patients’ physical condition, living habits, environmental factors and economic conditions as well as their recognition of this disease. It should be particularly emphasized that patients with unobvious symptoms and those who have had this disease for long shouldn’t be absent of mind and only care about whether urine routine has turned better. They should pay much attention to pathological changes of the renal parenchyma. Examinations such as isotope nephrogram and effective plasma flow of both kidneys are recommended, which are as important as general examinations.
Traditional Chinese Medicine can effectively treat renal functional damage in this disease and unlike hormone treatment, it doesn’t have any side effect. Then how can Chinese medicine treat this disease?
By its function of anti-inflammation, anti-allergy and anti-fibrosis of the glomeruli, traditional Chinese medicine can effectively change the condition of glomerular proliferation and effusion. It can gradually recover the renal functions by promoting fibrinolysis, reducing the agglomeration of the blood platelet and increasing GFR (Glomerular Filtration Rate). Through improving the permeability of the glomerular capillaries and increasing renal blood flow, Chinese medicine can recover the slightly or moderately damaged renal functions completely and partly recover the severely damaged renal functions. In addition, it can remit the renal atrophy to a certain extent.
Therefore, effective treatment of FPS IgA Nephropathy should be a combination of western medicine and Micro-Chinese Medicine Osmotherapy, with the former targeted at the anti-inflammatory treatment and the latter giving the radical treatment by reversing and repairing the damaged renal intrinsic cells, eliminating the excessive immune complex and at the same time providing the nutrition needed. By adopting these two methods, we can achieve a simultaneous treatment of both the symptoms and the essential disease. When the renal intrinsic cells are repaired, the inflammatory cells are inactivated and urine protein and occult blood have recovered to a normal range, then FPS IgA Nephropathy has achieved a systematic and standard treatment.
As is known to all, treatment of kidney disease is rather complicated. At present, there is no specific effective treatment of Focal Proliferative Sclerosing IgA Nephropathy in western medicine. Pure application of western medicines such as hormone, Tripterygium wilfordii and Cyclophosphamide in anti-inflammatory treatments cannot change the renal state of ischemia and anoxia, so it cannot effectively repair the glomerular filtration membrane and recover its filtration function to a normal state. Therefore, these medicines are just treating the symptoms of proteinuria and occult blood by transiently inhibiting the generation of various receptors and controlling the damage and progress of the inflammatory reaction for a short time. But they cannot achieve the key point of repairing the damaged renal intrinsic cells, so even though the symptoms may disappear after using these medicines, the root cause is still unchanged and deposition of immune complex will reoccur and cause proteinuria and occult blood. This is exactly the reason why the disease is easy to recur by western medicine treatment.
Then what’s the correct treating method?
Treatment of this disease should vary from the patients’ physical condition, living habits, environmental factors and economic conditions as well as their recognition of this disease. It should be particularly emphasized that patients with unobvious symptoms and those who have had this disease for long shouldn’t be absent of mind and only care about whether urine routine has turned better. They should pay much attention to pathological changes of the renal parenchyma. Examinations such as isotope nephrogram and effective plasma flow of both kidneys are recommended, which are as important as general examinations.
Traditional Chinese Medicine can effectively treat renal functional damage in this disease and unlike hormone treatment, it doesn’t have any side effect. Then how can Chinese medicine treat this disease?
By its function of anti-inflammation, anti-allergy and anti-fibrosis of the glomeruli, traditional Chinese medicine can effectively change the condition of glomerular proliferation and effusion. It can gradually recover the renal functions by promoting fibrinolysis, reducing the agglomeration of the blood platelet and increasing GFR (Glomerular Filtration Rate). Through improving the permeability of the glomerular capillaries and increasing renal blood flow, Chinese medicine can recover the slightly or moderately damaged renal functions completely and partly recover the severely damaged renal functions. In addition, it can remit the renal atrophy to a certain extent.
Therefore, effective treatment of FPS IgA Nephropathy should be a combination of western medicine and Micro-Chinese Medicine Osmotherapy, with the former targeted at the anti-inflammatory treatment and the latter giving the radical treatment by reversing and repairing the damaged renal intrinsic cells, eliminating the excessive immune complex and at the same time providing the nutrition needed. By adopting these two methods, we can achieve a simultaneous treatment of both the symptoms and the essential disease. When the renal intrinsic cells are repaired, the inflammatory cells are inactivated and urine protein and occult blood have recovered to a normal range, then FPS IgA Nephropathy has achieved a systematic and standard treatment.
2011年9月29日星期四
Is IgA Nephropathy Curable?
1. What is IgA Nephropathy?
IgA Nephropathy is a kidney disorder that occurs when IgA---a protein thathelps our bodies fight infections---settles in the kidneys. The disorder can occur suddenly (acute), or progress slowly over many years (choric glomerulonephritis). When itoccurs, the IgA deposits may cause the kidneys to leak blood and sometimes protein in the urine.
2. Is IgA Nephropathy curable?
As a matter of fact, kidney disease usually can not be cured. When the kidneys are damaged, they can not be repaired. Treatments usually focus on slowing the progression of the disease and preventing complications. Though IgA Nephropathy can not be cured completely, we can delay the progression and expect a good prognosis through effective treatments.
3. Is there any effective treatment for IgA Nephropathy?
The goal of treatment is to relieve symptoms and prevent or delay chronic renal failure.
The conventional treatment of IgA Nephropathy is pure Western Medicine. The using of hormone, cyclophosphamide and other Western medicine can achieve the effects of anti-inflammatory and anticoagulation in a short time. However, hormone can only relieve patient’s condition temporarily, and it has obvious side effects and is easy to relapse. Because Western Medicine can not achieve the effect of repairing the damaged renal intrinsic cells, and the renal fibrosis progression can not be blocked either, patient’s condition will aggravate as time goes on. When we are affected by some riskyfactors, such as colds, infections, diet, mood and others, IgA Nephropathy will relapse once again. In a word, Western Medicine can not treat IgA Nephropathy fundamentally.
In such cases, we can take into considerationTraditional Chinese Medicine. Micro-Chinese Medicine Osmotherapy of Shijiazhuang Kidney Disease Hospital is such an effective treatment of IgA Nephropathy. The therapeutic mechanism of Micro-Chinese Medicine Osmotherapy is that it can block the renal fibrosis, repair the damaged renal intrinsic cells and rebuild the renal functions. The significant character of Micro-Chinese Medicine Osmotherapy is that it can treat the disease fundamentally. Thus we can delay the progression of the disease.
2011年9月27日星期二
How Does Western Medicine Treat IgA Nephropathy?
How Does Western Medicine Treat IgA Nephropathy?There are several ways?Let us look at General treatment
I General treatment
For the gross hematuria patients who have had upper respiratory tract infection, they should be treated by with effective antibiotic. For the IgA nephropathy patients with high blood pressure, we should take active measures to control the high blood pressure to lest hemodynamics abnormality and vascular impairment which can aggravate the nephritis’ conditions. For those patients who suffer from repeated gross hematuria, tonsil resection operation can be considered. Some reports point out that 40% of IgA hematuria patients can remit after having their tonsils focus resected.
II Regulate immune response
Taking Prednisolone to treat IgA nephritis, there is a 40% remission rate of the disease; combing to use Dipyridamole, Cyclophosphamide and P:dilantin ( 5-6mg/kg per daydaily), the serum IgA level can be lowered; taking Cyclosporine A ( 5mg/kg per daydaily), then the protein level can be lowered.
III Remove the immune complex in the blood circulation
After removing the immune complex in the blood circulation and letting the IgA nephritis patients take bran-free food for 6 months to 4 year, the IgA in the blood can decline dramatically, the condition of urine protein and hematuria can also be improved. The usage of intal for 1.2g per daydaily can reduce the protein level.
IV Reduce the sedimentation of IgA at the mesangial area
Taking Daonil,200mg, 200mg dailyper day, for 4 months, C3, the alexin, increases and urine protein level decreases. The usage of icosapeptide pentanoate and fish oil for 1.6g daily per day can delay the deteriorations of renal functions offunctions of IgA nephropathy patients.
In the first two measures, clinical data show that treating patients only by with Western medicine can improve the conditions of protein, occult and blood pressure. However, it can only temporarily inhibit other complications, and when the patients come across colds, infections and other unfavorable factors, many other symptoms of the disease will appear again.
Among the 110 IgA nephrit patients who are receiving treatments in Shijiazhuang Kidney Disease Hospital, most of them are treated in with the above-mentioned traditional therapies at the early stage of the disease, but the repeated relapses trouble them. Yet, in Shijiazhuang Kidney Disease Hospital, after receiving combing treatment of Chinese and Western medicine with Micro-Chinese Medicine Osmotherapy, the tracking statistics show that 98% patients gain favorable curative effects and the illness usually don’t recur. The most important is that the Micro-Chinese osmotherapy can effect a fundamental and permanent cure. It can not only clear away the immune complex at the glomerular basement membrane, but also, at the same time, restore the damaged organization of kidney and renew the function of kidney.
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