I. How to regard hormone therapy in treating Nephrotic Syndrome?
We all know that hormone therapy is commonly used in treating kidney diseases including Nephrotic Syndrome. The reason is that hormone does have the effect of controlling the disease in a short time. However, many patients with kidney disease will turn pale at the mention of hormone. The reason lies in its side effects and its only curing the symptoms instead of the disease which will cause relapse of the disease once and again. Therefore, we shouldn’t arbitrarily judge hormone as good or bad. Moreover, we should use it carefully, such as avoiding stopping using it suddenly; otherwise, it will easily cause many side effects.
II. To make out whether we can treat NS without hormone, we should also know the pathogenesis of NS and how hormone takes effect in treating this disease.
Nephrotic Syndrome is a group of glomerulopathy that has similar pathological changes and clinical manifestations. The main changes are strengthened permeability of the glomerular membrane and decrease of GFR (Glomerular Filtration Rate). The typical manifestations include massive proteinuria, Hypoproteinemia, severe edema and Hyperlipemia.
Then how does hormone take effect in treating NS? Hormone has the function of inhibiting immunocytes and organic immunoreaction, so it can reduce damage of the renal intrinsic cells by immune complex. At the same time, it can protect intercellular matrix by balancing generation and degradation of polysaccharide. So hormone can effectively control the progress of the disease, especially the acute and active stage of NS.
Different pathological types of primary Nephrotic Syndrome should be treated with different application method of hormone, but the common adverse effect of it should be paid attention to: central obesity, high blood pressure, osteoporosis; digestive tract symptoms like nausea, vomiting and stress ulcer; spiritual symptoms like insomnia and excitation.
III. New therapy of treating Nephrotic Syndrome—significant effect of Micro-Chinese Medicine
Here, we can see that it is not easy to get rid of hormone completely. But don’t get discouraged, we have an effective way of avoid the side effects of hormone to a large extent—to combine hormone therapy with traditional Chinese medicine treatment, which has great power to reduce the side effects of hormone. Moreover, traditional Chinese medicine also has good curative effect in treating NS.
2011年10月10日星期一
2011年10月5日星期三
Will Nephrotic Syndrome Develop into Uremia
When people develop Nephrotic Syndrome, most of them would want to know whether this disease will develop into Uremia one day.
Before giving a definite answer, we should firstly know that Nephrotic Syndrome is not an independent disease, but a set of signs or symptoms of the glomerular disease, typically showing large amounts of proteinuria, edema, hyperlipidemia and hypoproteinemia. Therefore, Nephrotic Syndrome will not necessarily develop into Uremia, for Nephrotic Syndrome of different pathological types has different prognosis. That is to say, if patients have not received effective treatment, or if they suffered from this disease repeatedly, then, Nephrotic Syndrome will develop slowly and finally develop into Uremia.
2. Since we have received treatment, why does this disease still develop?
This is because the root cause of Nephrotic Syndrome has not been removed.
When our healthy nephron are damaged, we also lose some of the renal functions gradually. And with the worsening of our condition, the damaged nephron will also progress to necrosis, and this pathological damage process is named as renal fibrosis. When the renal fibrosis progress to its end stage, then Uremia occurs.
In treating Nephrotic Syndrome, if the treatment is not aimed at effectively blocking the renal fibrosis, even though the patients' condition can turn better by the treatment of hormones, cyclophosphamide and other medicines, it is just temporal, and this disease is still easy to relapse. The reason is that the Western Medicine only has the anti-inflammatory effect, and it can not treat this disease from the root. Therefore, patients still have the chance to suffer from Uremia.
3. Since there is a chance for Nephrotic Syndrome developing into Uremia, what treatment can we expect?
Absolutely, if we want to refuse this "extremely unpleasant invitation" of suffering from Uremia, an effective and fundamental treatment is necessary. In turn, this disease should be treated from the root cause.
Before giving a definite answer, we should firstly know that Nephrotic Syndrome is not an independent disease, but a set of signs or symptoms of the glomerular disease, typically showing large amounts of proteinuria, edema, hyperlipidemia and hypoproteinemia. Therefore, Nephrotic Syndrome will not necessarily develop into Uremia, for Nephrotic Syndrome of different pathological types has different prognosis. That is to say, if patients have not received effective treatment, or if they suffered from this disease repeatedly, then, Nephrotic Syndrome will develop slowly and finally develop into Uremia.
2. Since we have received treatment, why does this disease still develop?
This is because the root cause of Nephrotic Syndrome has not been removed.
When our healthy nephron are damaged, we also lose some of the renal functions gradually. And with the worsening of our condition, the damaged nephron will also progress to necrosis, and this pathological damage process is named as renal fibrosis. When the renal fibrosis progress to its end stage, then Uremia occurs.
In treating Nephrotic Syndrome, if the treatment is not aimed at effectively blocking the renal fibrosis, even though the patients' condition can turn better by the treatment of hormones, cyclophosphamide and other medicines, it is just temporal, and this disease is still easy to relapse. The reason is that the Western Medicine only has the anti-inflammatory effect, and it can not treat this disease from the root. Therefore, patients still have the chance to suffer from Uremia.
3. Since there is a chance for Nephrotic Syndrome developing into Uremia, what treatment can we expect?
Absolutely, if we want to refuse this "extremely unpleasant invitation" of suffering from Uremia, an effective and fundamental treatment is necessary. In turn, this disease should be treated from the root cause.
2011年10月4日星期二
Treating Nephrotic Syndrome without Using Hormone Therapy?
I. How to regard hormone therapy in treating Nephrotic Syndrome?
We all know that hormone therapy is commonly used in treating kidney diseases including Nephrotic Syndrome. The reason is that hormone does have the effect of controlling the disease in a short time. However, many patients with kidney disease will turn pale at the mention of hormone. The reason lies in its side effects and its only curing the symptoms instead of the disease which will cause relapse of the disease once and again. Therefore, we shouldn’t arbitrarily judge hormone as good or bad. Moreover, we should use it carefully, such as avoiding stopping using it suddenly; otherwise, it will easily cause many side effects.
II. To make out whether we can treat NS without hormone, we should also know the pathogenesis of NS and how hormone takes effect in treating this disease.
Nephrotic Syndrome is a group of glomerulopathy that has similar pathological changes and clinical manifestations. The main changes are strengthened permeability of the glomerular membrane and decrease of GFR (Glomerular Filtration Rate). The typical manifestations include massive proteinuria, Hypoproteinemia, severe edema and Hyperlipemia.
Then how does hormone take effect in treating NS? Hormone has the function of inhibiting immunocytes and organic immunoreaction, so it can reduce damage of the renal intrinsic cells by immune complex. At the same time, it can protect intercellular matrix by balancing generation and degradation of polysaccharide. So hormone can effectively control the progress of the disease, especially the acute and active stage of NS.
Different pathological types of primary Nephrotic Syndrome should be treated with different application method of hormone, but the common adverse effect of it should be paid attention to: central obesity, high blood pressure, osteoporosis; digestive tract symptoms like nausea, vomiting and stress ulcer; spiritual symptoms like insomnia and excitation.
III. New therapy of treating Nephrotic Syndrome—significant effect of Micro-Chinese Medicine
Here, we can see that it is not easy to get rid of hormone completely. But don’t get discouraged, we have an effective way of avoid the side effects of hormone to a large extent—to combine hormone therapy with traditional Chinese medicine treatment, which has great power to reduce the side effects of hormone. Moreover, traditional Chinese medicine also has good curative effect in treating NS.
We all know that hormone therapy is commonly used in treating kidney diseases including Nephrotic Syndrome. The reason is that hormone does have the effect of controlling the disease in a short time. However, many patients with kidney disease will turn pale at the mention of hormone. The reason lies in its side effects and its only curing the symptoms instead of the disease which will cause relapse of the disease once and again. Therefore, we shouldn’t arbitrarily judge hormone as good or bad. Moreover, we should use it carefully, such as avoiding stopping using it suddenly; otherwise, it will easily cause many side effects.
II. To make out whether we can treat NS without hormone, we should also know the pathogenesis of NS and how hormone takes effect in treating this disease.
Nephrotic Syndrome is a group of glomerulopathy that has similar pathological changes and clinical manifestations. The main changes are strengthened permeability of the glomerular membrane and decrease of GFR (Glomerular Filtration Rate). The typical manifestations include massive proteinuria, Hypoproteinemia, severe edema and Hyperlipemia.
Then how does hormone take effect in treating NS? Hormone has the function of inhibiting immunocytes and organic immunoreaction, so it can reduce damage of the renal intrinsic cells by immune complex. At the same time, it can protect intercellular matrix by balancing generation and degradation of polysaccharide. So hormone can effectively control the progress of the disease, especially the acute and active stage of NS.
Different pathological types of primary Nephrotic Syndrome should be treated with different application method of hormone, but the common adverse effect of it should be paid attention to: central obesity, high blood pressure, osteoporosis; digestive tract symptoms like nausea, vomiting and stress ulcer; spiritual symptoms like insomnia and excitation.
III. New therapy of treating Nephrotic Syndrome—significant effect of Micro-Chinese Medicine
Here, we can see that it is not easy to get rid of hormone completely. But don’t get discouraged, we have an effective way of avoid the side effects of hormone to a large extent—to combine hormone therapy with traditional Chinese medicine treatment, which has great power to reduce the side effects of hormone. Moreover, traditional Chinese medicine also has good curative effect in treating NS.
2011年10月1日星期六
Can Nephrotic Syndrome Be Cured with Hormone
Can Nephrotic Syndrome Be Cured with Hormone?Long-term use of hormone of great damage.
At present, Nephrotic Syndrome is mainly treated with hormone. And one of the most frequently asked questions by patients is "Can Nephrotic Syndrome be cured with hormone?". Before we announce the answer, let's have a clear knowing of the therapeutic effect of hormone first.
1. The therapeutic effect of hormone
The hormone therapy really has a good therapeutic effect: the anti-inflammatory effect of hormone is good. With hormones, the inflammatory response can be controlled in a short time, thus preventing further damages to the renal intrinsic cells. And for patients who are sensitive to hormones, the large amounts of proteinuria will disappear in a short time, and their urine protein will turn negative in several days or a month. Therefore, this therapy really relieves the patients' pain in a certain degree.
As hormone has a good therapeutic effect in treating Nephrotic Syndrome, then, does it means that Nephrotic Syndrome can be cured with hormone?
2. Can Nephrotic Syndrome be cured with hormone?
When the symptoms remit or disappear after the treatment, the dose of hormone will usually be decreased. And most patients would thought that they are going to be cured. However, after a long-term treatment, they only find that this disease begins to relapse again and again, and even worse, this disease will develop into End-Stage Kidney Disease in some patients. In a word, Nephrotic Syndrome can not be cured with hormone.
As the therapeutic effect of hormone is good, some patients would wonder why this disease cannot be cured by hormone therapy. Actually, as a kind of Western Medicine, hormone therapy is just a kind of symptomatic treatment. That is to say, in treating this disease, it is only aimed at the symptoms, but not the root—the damaged nephron. Though the urine protein has been decreased or has disappeared, the kidney lesions still exist, and when patients have colds or infections, this disease relapse. And every relapse will aggravate the pathological damages of the kidney, and finally lead to End-Stage Kidney Disease.
Therefore, hormone therapy is not the best option for patients with Nephrotic Syndrome. Now there is a new treatment which can treat Nephrotic Syndrome fundamentally. It uses Traditional Chinese Medicine without side effects, for the effective medicines are permeated into the kidney lesions by external application. In addition, this new treatment is aimed at repairing and rebuilding the renal function, thus treating this disease from the root. And this new treatment is named Micro-Chinese Medicine Osmotherapy in our hospital.
At present, Nephrotic Syndrome is mainly treated with hormone. And one of the most frequently asked questions by patients is "Can Nephrotic Syndrome be cured with hormone?". Before we announce the answer, let's have a clear knowing of the therapeutic effect of hormone first.
1. The therapeutic effect of hormone
The hormone therapy really has a good therapeutic effect: the anti-inflammatory effect of hormone is good. With hormones, the inflammatory response can be controlled in a short time, thus preventing further damages to the renal intrinsic cells. And for patients who are sensitive to hormones, the large amounts of proteinuria will disappear in a short time, and their urine protein will turn negative in several days or a month. Therefore, this therapy really relieves the patients' pain in a certain degree.
As hormone has a good therapeutic effect in treating Nephrotic Syndrome, then, does it means that Nephrotic Syndrome can be cured with hormone?
2. Can Nephrotic Syndrome be cured with hormone?
When the symptoms remit or disappear after the treatment, the dose of hormone will usually be decreased. And most patients would thought that they are going to be cured. However, after a long-term treatment, they only find that this disease begins to relapse again and again, and even worse, this disease will develop into End-Stage Kidney Disease in some patients. In a word, Nephrotic Syndrome can not be cured with hormone.
As the therapeutic effect of hormone is good, some patients would wonder why this disease cannot be cured by hormone therapy. Actually, as a kind of Western Medicine, hormone therapy is just a kind of symptomatic treatment. That is to say, in treating this disease, it is only aimed at the symptoms, but not the root—the damaged nephron. Though the urine protein has been decreased or has disappeared, the kidney lesions still exist, and when patients have colds or infections, this disease relapse. And every relapse will aggravate the pathological damages of the kidney, and finally lead to End-Stage Kidney Disease.
Therefore, hormone therapy is not the best option for patients with Nephrotic Syndrome. Now there is a new treatment which can treat Nephrotic Syndrome fundamentally. It uses Traditional Chinese Medicine without side effects, for the effective medicines are permeated into the kidney lesions by external application. In addition, this new treatment is aimed at repairing and rebuilding the renal function, thus treating this disease from the root. And this new treatment is named Micro-Chinese Medicine Osmotherapy in our hospital.
2011年9月26日星期一
Why Massive Proteinuria Appear in Nephrotic Syndrome
The emergence of proteinuria to the person's body is very bad,Why Massive Proteinuria Appear in Nephrotic Syndrome?
Influence of size of protein molecule. Glomerular capillary’s elimination of a certain substance is in inverse proportion to its effective molecular radius, so the larger the molecular weight, the less of it will be filtered out or just cannot be filtered out at all.
In general condition, less amount of plasma protein (for example, albumin) with 60~70 thousand Dalton molecular weight will be filtered out; plasma protein (for example, α1 lipoprotein) of which the molecular weight is more than 200 thousand Dalton cannot be filtered out while plasma protein with relatively small molecular weight (less than 40 thousand) such as muramidase, β2-mg and light chain of immune globulin etc. can be filtered out freely. The barrier function, of which the filtration varies with protein molecular weight, is called molecule-selective barrier (or mechanical barrier).
Why does massive protein appear in Nephrotic Syndrome? Another reason is that protein is electrically charged. Both the endothecium and exothecium of the glomerular basement membrane and the surface of endothelial and epithelial cells of the glomerular vascular loops as well as the mesangial membrane contain rich amount of glycosaminoglycan (heparin sulfate) and sialic acid, both of which can charge the glomerular filtration membrane with negative charge and form the electrostatic barrier. By principle of “like charges repel”, clearance rate of protein with negative charges is the lowest and protein with positive charges the highest.
Influence of size of protein molecule. Glomerular capillary’s elimination of a certain substance is in inverse proportion to its effective molecular radius, so the larger the molecular weight, the less of it will be filtered out or just cannot be filtered out at all.
In general condition, less amount of plasma protein (for example, albumin) with 60~70 thousand Dalton molecular weight will be filtered out; plasma protein (for example, α1 lipoprotein) of which the molecular weight is more than 200 thousand Dalton cannot be filtered out while plasma protein with relatively small molecular weight (less than 40 thousand) such as muramidase, β2-mg and light chain of immune globulin etc. can be filtered out freely. The barrier function, of which the filtration varies with protein molecular weight, is called molecule-selective barrier (or mechanical barrier).
Why does massive protein appear in Nephrotic Syndrome? Another reason is that protein is electrically charged. Both the endothecium and exothecium of the glomerular basement membrane and the surface of endothelial and epithelial cells of the glomerular vascular loops as well as the mesangial membrane contain rich amount of glycosaminoglycan (heparin sulfate) and sialic acid, both of which can charge the glomerular filtration membrane with negative charge and form the electrostatic barrier. By principle of “like charges repel”, clearance rate of protein with negative charges is the lowest and protein with positive charges the highest.
2011年9月25日星期日
Why do Nephrotic Syndrome Patients Develop Edema?
Why do Nephrotic Syndrome Patients Develop Edema? This is us today to write.Treatment for kidney disease, enjoy healthy life.
I Fluid and sodium retention caused by low glomerular filtration rate;
II The fluid is likely to flow into tissue space from vessels due to the increased capillary permeability;
III Plasma colloid osmotic pressure decreases because of low albumin, and then the blood is likely to flow into tissue space;
IV Secondary aldosterone increases because of decrease of effective blood volume, which also aggravates the fluid and sodium retention.
Human beings’ kidneys have strong compensatory capacity, which means that kidneys have already be damaged in a certain degree when nephrotic edema occurs. We must pay attention to even slight edema, check up and treat it as soon as possible.
Treatment for kidney disease, enjoy healthy life.
www.nephrotic-syndrome.org
I Fluid and sodium retention caused by low glomerular filtration rate;
II The fluid is likely to flow into tissue space from vessels due to the increased capillary permeability;
III Plasma colloid osmotic pressure decreases because of low albumin, and then the blood is likely to flow into tissue space;
IV Secondary aldosterone increases because of decrease of effective blood volume, which also aggravates the fluid and sodium retention.
Human beings’ kidneys have strong compensatory capacity, which means that kidneys have already be damaged in a certain degree when nephrotic edema occurs. We must pay attention to even slight edema, check up and treat it as soon as possible.
Treatment for kidney disease, enjoy healthy life.
www.nephrotic-syndrome.org
2011年9月24日星期六
High-Vitamin Diet for Nephrotic Syndrome Patients
Nephrotic Syndrome Patients should pay attention to diet.
Vitamin plays a part in the energy metabolism of our human body, and the deficiency of it can
cause disorders of energy metabolism. Many blood coagulation factors and anticoagulation factors
are vitamin K-dependent. And the deficiency of the two factors will affect the hemostatic process
and the blood coagulation process. Vitamin D plays an important role in regulating calcium and
phosphorus metabolism. And folic acid and vitamin B6 also play a part in treating kidney disease.
In patients with Nephrotic Syndrome, no matter renal impairment or Renal Failure, all these
changes of the renal function will cause vitamin metabolism disorders, especially when
glucocorticoid is adopted in treating Childhood Nephrotic Syndrome.
When people develop Nephrotic Syndrome, the absorption and metabolism of vitamin will be affected
by the medicines the patients take, thus affecting the normal physiological activities of the
patients and further aggravating the patients' condition. In addition, vitamin can not be
synthesized in our human body, but is mainly supplemented by diets. Therefore, patients with
Nephrotic Syndrome should supplement enough vitamins by taking high-vitamin diet.
2. What is high-vitamin diet?
In order to supplement vitamins, patients with Nephrotic Syndrome just need to pay attention to
their daily diet. Generally, fresh vegetables and fruits are rich in vitamins, such as pears,
apples, tomatoes, cucumbers, etc.
As for vitamin D, which relates to Hypertension and the absorption of calcium and phosphorus,
patients with Nephrotic Syndrome should especially pay attention to. Cod liver oil is the food
which contains vitamin D most.
Vitamin plays a part in the energy metabolism of our human body, and the deficiency of it can
cause disorders of energy metabolism. Many blood coagulation factors and anticoagulation factors
are vitamin K-dependent. And the deficiency of the two factors will affect the hemostatic process
and the blood coagulation process. Vitamin D plays an important role in regulating calcium and
phosphorus metabolism. And folic acid and vitamin B6 also play a part in treating kidney disease.
In patients with Nephrotic Syndrome, no matter renal impairment or Renal Failure, all these
changes of the renal function will cause vitamin metabolism disorders, especially when
glucocorticoid is adopted in treating Childhood Nephrotic Syndrome.
When people develop Nephrotic Syndrome, the absorption and metabolism of vitamin will be affected
by the medicines the patients take, thus affecting the normal physiological activities of the
patients and further aggravating the patients' condition. In addition, vitamin can not be
synthesized in our human body, but is mainly supplemented by diets. Therefore, patients with
Nephrotic Syndrome should supplement enough vitamins by taking high-vitamin diet.
2. What is high-vitamin diet?
In order to supplement vitamins, patients with Nephrotic Syndrome just need to pay attention to
their daily diet. Generally, fresh vegetables and fruits are rich in vitamins, such as pears,
apples, tomatoes, cucumbers, etc.
As for vitamin D, which relates to Hypertension and the absorption of calcium and phosphorus,
patients with Nephrotic Syndrome should especially pay attention to. Cod liver oil is the food
which contains vitamin D most.
2011年9月23日星期五
Why Do Nephrotic Syndrome Patients Need to Keep Away from Colds?
Patients with nephrotic syndrome to a cold, cold away from the very dangerous.
1. Actually, it does has relation with Nephrotic Syndrome.
By the stimulation of various infectious agents(such as virus, bacteria, dust, etc.), the immune
system of our human body will be activated, thus producing inflammation response to resist the
"external invasion". And new-type antigen-antibody response will form in the kidneys, which will
form large amounts of immune complexes depositing in the blood vessels of the kidneys, thus
causing ischemia and hypoxia of the kidney tissues. The ischemia and hypoxia will further cause
kidney tissue fibrosis, thus aggravating the patients' condition.
Nephrotic Syndrome is easy to relapse after colds. And among the complications of Nephrotic
Syndrome, colds is the most common one, and is also easy to be neglected, thus the patients'
condition are easy to be aggravated. Therefore, preventing colds is of great importance for
patients with Nephrotic Syndrome.
2. How to prevent colds?
· Steaming vinegar 15~20 minutes every day indoors
It can kill or restrain the germs indoors.
· Washing face with cold water, and taking a footbath with hot water every day can help increase
the body resistance.
· In the influenza seasons, taking some medicines for preventing colds.
· Using weak-salt water to gargle after meals every day
This method can help eliminate the oral bacteria.
1. Actually, it does has relation with Nephrotic Syndrome.
By the stimulation of various infectious agents(such as virus, bacteria, dust, etc.), the immune
system of our human body will be activated, thus producing inflammation response to resist the
"external invasion". And new-type antigen-antibody response will form in the kidneys, which will
form large amounts of immune complexes depositing in the blood vessels of the kidneys, thus
causing ischemia and hypoxia of the kidney tissues. The ischemia and hypoxia will further cause
kidney tissue fibrosis, thus aggravating the patients' condition.
Nephrotic Syndrome is easy to relapse after colds. And among the complications of Nephrotic
Syndrome, colds is the most common one, and is also easy to be neglected, thus the patients'
condition are easy to be aggravated. Therefore, preventing colds is of great importance for
patients with Nephrotic Syndrome.
2. How to prevent colds?
· Steaming vinegar 15~20 minutes every day indoors
It can kill or restrain the germs indoors.
· Washing face with cold water, and taking a footbath with hot water every day can help increase
the body resistance.
· In the influenza seasons, taking some medicines for preventing colds.
· Using weak-salt water to gargle after meals every day
This method can help eliminate the oral bacteria.
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